Difference between revisions of "Syphilis"

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==Microscopic==
==Microscopic==
Features:
Features:
*Spirochetes - '''key feature'''.
*Plasma cells - '''key feature'''.<ref name=pmid18948765>{{Cite journal  | last1 = Brinster | first1 = NK. | title = Dermatopathology for the surgical pathologist: a pattern-based approach to the diagnosis of inflammatory skin disorders (part II). | journal = Adv Anat Pathol | volume = 15 | issue = 6 | pages = 350-69 | month = Nov | year = 2008 | doi = 10.1097/PAP.0b013e31818b1ac6 | PMID = 18948765 }}</ref>
*Spirochetes - '''diagnostic'''.
*+/-[[Granulomas]]<ref name=Ref_PCPBoD8_47>{{Ref PCPBoD8|47}}</ref> - ''gumma'' - in the tertiary phase.<ref>URL: [http://pediatrics.aappublications.org/cgi/content/full/104/1/e4 http://pediatrics.aappublications.org/cgi/content/full/104/1/e4]. Accessed on: 17 November 2010.</ref>
*+/-[[Granulomas]]<ref name=Ref_PCPBoD8_47>{{Ref PCPBoD8|47}}</ref> - ''gumma'' - in the tertiary phase.<ref>URL: [http://pediatrics.aappublications.org/cgi/content/full/104/1/e4 http://pediatrics.aappublications.org/cgi/content/full/104/1/e4]. Accessed on: 17 November 2010.</ref>


Useful [[stains]]:
Useful [[stains]]:

Revision as of 02:36, 20 September 2011

Syphilis is the infectious disease caused by Treponema pallidum.

Microscopic

Features:

  • Plasma cells - key feature.[1]
  • Spirochetes - diagnostic.
  • +/-Granulomas[2] - gumma - in the tertiary phase.[3]


Useful stains:

Image: Dieterle stain - T. pallidum (WC).

See also

References

  1. Brinster, NK. (Nov 2008). "Dermatopathology for the surgical pathologist: a pattern-based approach to the diagnosis of inflammatory skin disorders (part II).". Adv Anat Pathol 15 (6): 350-69. doi:10.1097/PAP.0b013e31818b1ac6. PMID 18948765.
  2. Mitchell, Richard; Kumar, Vinay; Fausto, Nelson; Abbas, Abul K.; Aster, Jon (2011). Pocket Companion to Robbins & Cotran Pathologic Basis of Disease (8th ed.). Elsevier Saunders. pp. 47. ISBN 978-1416054542.
  3. URL: http://pediatrics.aappublications.org/cgi/content/full/104/1/e4. Accessed on: 17 November 2010.