Difference between revisions of "Starvation"

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(→‎Gross: +micro)
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==Gross==
==Gross==
*Serous atrophy:<ref name=pmid19567708>{{cite journal |author=Munfus DL, Menke DM |title=Case of severe serous fat atrophy |journal=Mayo Clin. Proc. |volume=84 |issue=7 |pages=570 |year=2009 |month=July |pmid=19567708 |pmc=2704126 |doi=10.4065/84.7.570 |url=http://www.mayoclinicproceedings.com/content/84/7/570.full}}</ref>
*Serous fat atrophy:<ref name=pmid19567708>{{cite journal |author=Munfus DL, Menke DM |title=Case of severe serous fat atrophy |journal=Mayo Clin. Proc. |volume=84 |issue=7 |pages=570 |year=2009 |month=July |pmid=19567708 |pmc=2704126 |doi=10.4065/84.7.570 |url=http://www.mayoclinicproceedings.com/content/84/7/570.full}}</ref>
**Soft brown/[[myxoid]] material replaces fat.
**Soft brown/[[myxoid]] material replaces fat.
==Microscopic==
Features:
*Globular cells 3-4x a RBC with:
**Clear cytoplasm.
**One small peripheral nucleus.
DDx:
*[[Signet ring cell carcinoma]].<ref name=pmid6222282>{{Cite journal  | last1 = Clarke | first1 = BE. | last2 = Brown | first2 = DJ. | last3 = Xipell | first3 = JM. | title = Gelatinous transformation of the bone marrow. | journal = Pathology | volume = 15 | issue = 1 | pages = 85-8 | month = Jan | year = 1983 | doi =  | PMID = 6222282 }}</ref>
Images:
*[http://commons.wikimedia.org/wiki/File:Fat_atrophy_-_intermed_mag.jpg Serous fat atrophy - intermed mag. (WC)].
*[http://commons.wikimedia.org/wiki/File:Fat_atrophy_-_very_high_mag.jpg Serous fat atrophy - very high mag. (WC)].


==Associations<ref name=pmid19567708/>==
==Associations<ref name=pmid19567708/>==

Revision as of 05:07, 29 March 2012

Starvation is due to lack of food, inability or lack of desire to eat.

Gross

  • Serous fat atrophy:[1]
    • Soft brown/myxoid material replaces fat.

Microscopic

Features:

  • Globular cells 3-4x a RBC with:
    • Clear cytoplasm.
    • One small peripheral nucleus.

DDx:

Images:

Associations[1]

  • Acute febrile states.
  • AIDS.
  • Alcoholism.
  • Anorexia nervosa.
  • Cachexia.
  • Carcinomas.
  • Chronic heart failure.
  • Lymphoma.

See also

References

  1. 1.0 1.1 Munfus DL, Menke DM (July 2009). "Case of severe serous fat atrophy". Mayo Clin. Proc. 84 (7): 570. doi:10.4065/84.7.570. PMC 2704126. PMID 19567708. http://www.mayoclinicproceedings.com/content/84/7/570.full.
  2. Clarke, BE.; Brown, DJ.; Xipell, JM. (Jan 1983). "Gelatinous transformation of the bone marrow.". Pathology 15 (1): 85-8. PMID 6222282.