Lymph node pathology

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This article deals with lymph node pathology. An introduction to the lymph node is in the lymph nodes article.

Kikuchi disease

General

  • AKA histiocytic necrotising lymphadenitis.[1]
  • Rare disease that may mimic cancer, esp. lymphoma.
  • Treatment: oral corticosteroids.

Micrograph

Features:[2]

  • Necrosis.
  • Histiocytes.

IHC

  • CD68 +ve.
  • CD20, CD3, and CD30 - mixed.
    • Done to excluded lymphoma; should show a mixed population of lymphocytes.

See also

References

  1. ↑ Kaushik V, Malik TH, Bishop PW, Jones PH (June 2004). "Histiocytic necrotising lymphadenitis (Kikuchi's disease): a rare cause of cervical lymphadenopathy". Surgeon 2 (3): 179–82. PMID 15570824.
  2. ↑ URL: http://www.ispub.com/journal/the_internet_journal_of_head_and_neck_surgery/volume_1_number_1_30/article_printable/kikuchi_s_lymphadenitis_in_a_young_male.html. Accessed on: 1 June 2010.
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