Hyperplastic polyp with perineuromatous stroma
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Hyperplastic polyp with perineuromatous stroma, also known as benign serrated colorectal fibroblastic polyps/intramucosal perineurioma and hybrid hyperplastic polyp/mucosal perineurioma, is a benign colorectal polyp.
General
- Rare.
- Benign.[1]
Microscopic
Features:
- Serrated epithelial cells (at the surface of the gland) - key feature.
- Serrated appearance = saw-tooth appearance, epithelium has jagged edge.
- Perineuromatous stroma.
DDx:
See also
References
- ↑ Agaimy, A.; Stoehr, R.; Vieth, M.; Hartmann, A. (Nov 2010). "Benign serrated colorectal fibroblastic polyps/intramucosal perineuriomas are true mixed epithelial-stromal polyps (hybrid hyperplastic polyp/mucosal perineurioma) with frequent BRAF mutations.". Am J Surg Pathol 34 (11): 1663-71. doi:10.1097/PAS.0b013e3181f4a458. PMID 20962618.