Tumour suppressor gene
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A tumour suppressor gene is a gene that acts to protect the organism which it is within from developing cancer.
Examples
Tumour suppressors:
| Gene | Syndrome or disease |
|---|---|
| TP53 (p53)[1] | Li-Fraumeni syndrome |
| BRCA1[2] | Familial breast-ovarian cancer 1 |
| RB1[3] | |
| VHL[4] | Von Hippel-Lindau disease |
| NF1[5] | Neurofibromatosis type 1 |