Negative prostatectomy

Negative prostatectomy, also radical prostatectomy without cancer, occasionally happens.

General

• Seen in approximately 1% of prostatectomies.

Work-up

1. Review biopsy if available.
   • Is it plausible?
     • Biopsies in negative prostatectomies or minimal cancer prostatectomies usually have a small volume of low grade cancer.
     • A negative prostatectomy with high-grade cancer on biopsy or a large volume of disease on biopsy should prompt identity testing.
2. Submit prostate in total (if not already done).
3. Levels (x3) on all prostate blocks.
4. Flip the (prostate tissue) blocks and do levels (x3).

See also

• Prostate cancer.
• Negative LEEP.