Eosinophilic gastritis

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Eosinophilic gastritis, abbreviated EG, is an uncommon inflammatory process of stomach characterized by abundant eosinophils.

General

Rare.

Gross

+/-Snakeskin appearance.

DDx:

Portal hypertensive gastropathy.

Microscopic

Features:

Abundant eosinophils -- >=127 eosinophils/mm².^[1]
- 30 eosinophils/HPF, if the field diameter of 1 HPF is 0.55 mm.

Notes:

Normal range:^[1]
- <38 eosinophils/mm².
  - Typically ~16 eosinophils/mm².
Mild eosinophilia is seen in:^[1]
- Crohn's disease ~ 31 eosinophils/mm² (range: 0-203 eosinophils/mm²).
- Helicobacter gastritis ~ 25 eosinophils/mm² (range: 0-219 eosinophils/mm²).

See also

References

↑ ^1.0 ^1.1 ^1.2 Lwin, T.; Melton, SD.; Genta, RM. (Apr 2011). "Eosinophilic gastritis: histopathological characterization and quantification of the normal gastric eosinophil content.". Mod Pathol 24 (4): 556-63. doi:10.1038/modpathol.2010.221. PMID 21169993.

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