Ethanol abuse
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Ethanol abuse is the excessive consumption of ethyl alcohol or ethanol.
In common usage, alcohol is used as a synonym for ethanol, which is abbreviated EtOH. Alcohol abuse causes varies medical problems.
In pathology, alcohol may refer to the fixative; it is a chemical used to preserve tissue.
General
- Very common.
Classic lab findings in alcohol abusers
- AST & ALT elevated with AST:ALT=2:1.
- GGT elevated.
- MCV increased.
Pathology associated with alcohol
Liver:
- Alcoholic liver disease.
- Alcoholic steatohepatitis.
- Liver steatosis, macrovesicular and centrilobular.
- Cirrhosis, micronodular.
CNS:
- Marchiafava-Bignami Disease.
- Wernicke's encephalopathy.
- Intracranial haemorrhage - due to trauma arising from drunkenness.