MUTYH polyposis syndrome

MYH polyposis syndrome, also MUTYH polyposis syndrome, is an autosomal recessive syndrome characterized by numerous polyps and an increased risk of colorectal carcinoma.

The MUTYH gene is a mismatch repair gene. Mutations lead to defective base excision repair - specifically more transversions.

See also

• Familial adenomatous polyposis.

External links

• [http://journal.nzma.org.nz/journal/121-1287/3419/

MYH-associated polyposis—a new familial colorectal cancer syndrome without a family history (nzma.org.nz)].