Testicular adrenal rest tumour
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Testicular adrenal rest tumour, abbreviated TART, is a rare tumour associated with increased ACTH, typically seen in the context of congenital adrenal hyperplasia.[1]
General
- Very rare.
Clinical:
- Serum ACTH elevated.
Gross
- Bilateral testicular masses.
Microscopic
Features:
- Nests of eosinophilic cells interspersed with thin bands of fibrous tissue.
- Mild (endocrine) nuclear atypia.
DDx:
- Leydig cell tumour - history different.
Images
IHC
- Melan A +ve.[2]
See also
References
- ↑ Olpin, JD.; Witt, B. (Feb 2014). "Testicular adrenal rest tumors in a patient with congenital adrenal hyperplasia.". J Radiol Case Rep 8 (2): 46-53. doi:10.3941/jrcr.v8i2.1489. PMID 24967019.
- ↑ Mizukami, H.; Hamamatsu, A.; Mori, S.; Hara, S.; Kuroda, M.; Nagai, T.; Fukunaga, T. (Mar 2011). "Autopsy and genetic diagnosis of 21-hydroxylase deficiency with bilateral testicular tumors in a case under no medication for over one year.". Forensic Sci Int 206 (1-3): e71-5. doi:10.1016/j.forsciint.2010.09.017. PMID 20951518.