Dysembryoplastic neuroepithelial tumour
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Dysembryoplastic neuroepithelial tumour, abbreviated DNET[1] and DNT,[2] is a rare neuropathology tumour that is associated with epilepsy.
General
Gross/radiology
- Temporal lobe.
- Variable architecture:[4] cystic, solitary nodular, multinodular.
Microscopic
Features:[4]
- Cells similar to oligodendrocytes:
- Large central nuclei with indentations.
- Multiple small nucleoli (common).
- Clear cytoplasm.
DDx:
- Oligodendroglioma.
- These have rounder, smaller nuclei with occasional nucleoli.[4]
Images
DNT. (WC/Sbrandner)
www:
See also
References
- ↑ Alexander, H.; Tannenburg, A.; Walker, DG.; Coyne, T. (Jan 2015). "Progressive dysembryoplastic neuroepithelial tumour.". J Clin Neurosci 22 (1): 221-4. doi:10.1016/j.jocn.2014.07.022. PMID 25311417.
- ↑ Matyja, E.; Grajkowska, W.; Kunert, P.; Marchel, A. (Oct 2014). "A peculiar histopathological form of dysembryoplastic neuroepithelial tumor with separated pilocytic astrocytoma and rosette-forming glioneuronal tumor components.". Neuropathology 34 (5): 491-8. doi:10.1111/neup.12124. PMID 24735014.
- ↑ Cataltepe, O.; Turanli, G.; Yalnizoglu, D.; Topçu, M.; Akalan, N. (Apr 2005). "Surgical management of temporal lobe tumor-related epilepsy in children.". J Neurosurg 102 (3 Suppl): 280-7. doi:10.3171/ped.2005.102.3.0280. PMID 15881751.
- ↑ 4.0 4.1 4.2 O'Brien, DF.; Farrell, M.; Delanty, N.; Traunecker, H.; Perrin, R.; Smyth, MD.; Park, TS. (Dec 2007). "The Children's Cancer and Leukaemia Group guidelines for the diagnosis and management of dysembryoplastic neuroepithelial tumours.". Br J Neurosurg 21 (6): 539-49. doi:10.1080/02688690701594817. PMID 18071981.