Cribriform pattern within invasive prostate carcinoma
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Cribriform pattern within invasive prostate carcinoma has been shown to be poor prognosticator in prostate cancer.[1]
Microscopic
Features:[citation needed]
- Cribriform architecture.
- Loss of basal cells.
Note:
- In the morphologic context, invasive cribriform carcinoma may be lumped with intraductal carcinoma of the prostate, as immunostains are required to differentiate.[2]
See also
References
- ↑ Iczkowski, KA.; Paner, GP.; Van der Kwast, T. (Jan 2018). "The New Realization About Cribriform Prostate Cancer.". Adv Anat Pathol 25 (1): 31-37. doi:10.1097/PAP.0000000000000168. PMID 28820750.
- ↑ Kweldam CF, Kümmerlin IP, Nieboer D, Steyerberg EW, Bangma CH, Incrocci L, van der Kwast TH, Roobol MJ, van Leenders GJ (August 2017). "Presence of invasive cribriform or intraductal growth at biopsy outperforms percentage grade 4 in predicting outcome of Gleason score 3+4=7 prostate cancer". Mod. Pathol. 30 (8): 1126–1132. doi:10.1038/modpathol.2017.29. PMID 28530220.