Ber-EP4
Ber-EP4 is a commonly available immunostain.
Positive
- Basal cell carcinoma.
- Lung adenocarcinoma (55 of 59 cases[1]).
Negative
- Squamous cell carcinoma of the skin.[2]
- Malignant mesothelioma (18 of 70 cases[1]).
- Microcystic adnexal carcinoma.[3]
See also
References
- ↑ 1.0 1.1 Ordóñez, NG. (Jan 1998). "Value of the Ber-EP4 antibody in differentiating epithelial pleural mesothelioma from adenocarcinoma. The M.D. Anderson experience and a critical review of the literature.". Am J Clin Pathol 109 (1): 85-9. PMID 9426522.
- ↑ Yu, L.; Galan, A.; McNiff, JM. (Oct 2009). "Caveats in BerEP4 staining to differentiate basal and squamous cell carcinoma.". J Cutan Pathol 36 (10): 1074-176. doi:10.1111/j.1600-0560.2008.01223.x. PMID 19187107.
- ↑ Sellheyer, K.; Nelson, P.; Kutzner, H.; Patel, RM. (Apr 2013). "The immunohistochemical differential diagnosis of microcystic adnexal carcinoma, desmoplastic trichoepithelioma and morpheaform basal cell carcinoma using BerEP4 and stem cell markers.". J Cutan Pathol 40 (4): 363-70. doi:10.1111/cup.12085. PMID 23398472.