Histology artifacts
Histology artifacts are common.
Cautery artifact
Main article: Cautery artifact
Tissue fold
- Darker well demarcated line with apparent disruption of the architecture.
Tissue fold (center of image) in basal cell hyperplasia of the prostate.
Extensive tissue folding in a SSA.
Chatter artifact
- Fine parallel lines.
Chatter artifact in tubular adenoma.
Chatter artifact in complex endometrial hyperplasia.
Chatter artifact in TILs.
Tissue tearing
- Usually due to something intrinsic to the tissue that is hard, e.g. calcium.
Tearing due to a calcification.
Sponge artifact
- Little squares of tissue in a regular pattern.
Bubble artifact
Large
- Large bubbles of air under the cover slip.