Anal squamous cell carcinoma
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Anal squamous cell carcinoma is a type of anal cancer.
It is also known as anal squamous carcinoma and squamous cell carcinoma of the anus.
General
- Most common form of anal cancer.
Risk factors:[1]
- Men who have sex with men.
- Immunosuppressed.
- HIV infection.
Microscopic
Features:
Anus Squamous Cell Carcinoma (Non Keratinizing) - (SKB)
Anus Squamous Cell Carcinoma (Non Keratinizing) - (SKB)
Anus Squamous Cell Carcinoma (Non Keratinizing or shall we say poorly keratinizing as there are squamatized nests focally at high power) - (SKB)
DDx:
- Anal gland adenocarcinoma.
- Poorly differentiated rectal adenocarcinoma.
IHC
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RECTUM, DISTAL, BIOPSY: - INVASIVE SQUAMOUS CELL CARCINOMA.
See also
- Anus.
References
- ↑ Kutlubay, Z.; Engin, B.; Zara, T.; Tüzün, Y.. "Anogenital malignancies and premalignancies: Facts and controversies.". Clin Dermatol 31 (4): 362-73. doi:10.1016/j.clindermatol.2013.01.003. PMID 23806153.
- ↑ 2.0 2.1 Gunia, S.; Koch, S.; May, M. (Feb 2013). "Is CDX2 immunostaining useful for delineating anorectal from penile/vulvar squamous cancer in the setting of squamous cell carcinoma with clinically unknown primary site presenting with histologically confirmed inguinal lymph node metastasis?". J Clin Pathol 66 (2): 109-12. doi:10.1136/jclinpath-2012-201138. PMID 23105122.