Granulation tissue

Granulation tissue forms when wound heal.

Gross

• Looks granular, ergo the name granulation tissue.

Image:

• Granulation (WC).

Microscopic

Features:

• Blood vessel rich - key element.
  • Small size ~ 25 micrometers in diameter.^{[citation needed]}
• Proliferation of fibroblasts - key element.
• Inflammation - especially lymphocytes.
  • Plasma cells common.

DDx:

• Mucocele.
• Pyogenic granuloma.
• Traumatized hemangioma.

Images:

• Granulation tissue with entrapped muscle (jhmi.edu).
• Granulation tissue (siumed.edu).

See also

• Basics.