Difference between revisions of "Intranodal palisaded myofibroblastoma"
Jump to navigation
Jump to search
(→Microscopic: +wc images) |
m (→Microscopic) |
||
| Line 10: | Line 10: | ||
Features: | Features: | ||
#Rim of peripheral lymphoid tissue. | #Rim of peripheral lymphoid tissue. | ||
#*Remnant of [[lymph node]]. | |||
#Spindle cells with nuclear palisading - '''key feature'''. | #Spindle cells with nuclear palisading - '''key feature'''. | ||
#RBC extravasation/hemorrhage. | #RBC extravasation/hemorrhage. | ||
Revision as of 23:44, 9 October 2011
Intranodal palisaded myofibroblastoma, abbreviated IPM, is a rare tumour that classically presents as an inguinal mass.[1]
General
- Rare.
- Male:female = 2:1.
- Adults - middle age.
- Treatment: simple excision; rare recurrences have been reported.[2]
Microscopic
Features:
- Rim of peripheral lymphoid tissue.
- Remnant of lymph node.
- Spindle cells with nuclear palisading - key feature.
- RBC extravasation/hemorrhage.
- Amianthoid fibers - blood vessel surrounded by collagen with (fine) peripheral spokes.[3]
- Intracellular and extracellular fuchsinophilic bodies.
- Smooth muscle actin +ve.
DDx:
Notes:
- Fuchsinophilic = affinity for the acid dye fuchsin.[4]
- Image: Fuchsinophilic material (flickr.com) - red.
Images:
- www:
- WC:
IHC
- SMA +ve.
- Cyclin D1 +ve.
Other:
- S100 -ve
- Excludes schwannoma.
- GFAP -ve.
- CD34 -ve.
- Desmin -ve
- Ki-67 - low.
See also
References
- ↑ Nguyen, T.; Eltorky, MA. (Feb 2007). "Intranodal palisaded myofibroblastoma.". Arch Pathol Lab Med 131 (2): 306-10. doi:10.1043/1543-2165(2007)131[306:IPM]2.0.CO;2. PMID 17284119.
- ↑ Creager, AJ.; Garwacki, CP. (May 1999). "Recurrent intranodal palisaded myofibroblastoma with metaplastic bone formation.". Arch Pathol Lab Med 123 (5): 433-6. doi:10.1043/0003-9985(1999)1230433:RIPMWM2.0.CO;2. PMID 10235504.
- ↑ 3.0 3.1 Bigotti, G.; Coli, A.; Mottolese, M.; Di Filippo, F. (Sep 1991). "Selective location of palisaded myofibroblastoma with amianthoid fibres.". J Clin Pathol 44 (9): 761-4. PMID 1918406.
- ↑ URL: http://www.merriam-webster.com/medical/fuchsinophilic. Accessed on: 3 October 2011.