Difference between revisions of "Adenosquamous carcinoma of the lung"

From Libre Pathology
Jump to navigation Jump to search
(→‎www: +SO)
Line 58: Line 58:
*[http://www.webpathology.com/image.asp?case=415&n=21 Lung adenosquamous carcinoma (webpathology.com)].
*[http://www.webpathology.com/image.asp?case=415&n=21 Lung adenosquamous carcinoma (webpathology.com)].
*[https://www.flickr.com/photos/pulmonary_pathology/7491350926/ Lung adenosquamous carcinoma (flickr.com/Yale Rosen)].
*[https://www.flickr.com/photos/pulmonary_pathology/7491350926/ Lung adenosquamous carcinoma (flickr.com/Yale Rosen)].
==Sign out==
===Biopsy - possible adenosquamous carcinoma===
<pre>
Left Upper Lobe of Lung, Core Biopsy:
    - NONSMALL CELL CARCINOMA, FAVOUR ADENOCARCINOMA, CANNOT EXCLUDE ADENOSQUAMOUS CARCINOMA.
Comment:
The tumour stains as follow:
POSITIVE: TTF-1, CK5/6 (focal), p63, napsin A.
NEGATIVE: (none).
The positive staining (TTF-1 and napsin A versus CK5/6 and p63) appears to be in different tumour cells. 
The case was reviewed internally and there is agreement on the above interpretation.
</pre>
Note:
*Cases should not be signed as ''adenosquamous carcinoma'' on biopsy, due to the percentage requirements of the diagnosis.


==See also==
==See also==

Revision as of 16:50, 22 December 2017

Adenosquamous carcinoma of the lung
Diagnosis in short

Adenosquamous carcinoma of lung. H&E stain.
LM DDx squamous cell carcinoma of the lung, adenocarcinoma of the lung
Site lung - see lung tumours
Prevalence rare
Clin. DDx other lung tumours

Adenosquamous carcinoma of the lung, also lung adenosquamous carcinoma, is a rare epithelial derived malignancy of the lung with features of both adenocarcinoma and squamous cell carcinoma.

It is grouped with the non-small cell lung cancers.

General

Microscopic

Features:

  1. Adenocarcinoma component.
  2. Squamous cell carcinoma component.

DDx:

Images

  • ASC - intermed. mag. (WC)

  • ASC - intermed. mag. (WC)

  • ASC - high mag. (WC)

  • ASC - very high mag. (WC)

www

Sign out

Biopsy - possible adenosquamous carcinoma

Left Upper Lobe of Lung, Core Biopsy:
     - NONSMALL CELL CARCINOMA, FAVOUR ADENOCARCINOMA, CANNOT EXCLUDE ADENOSQUAMOUS CARCINOMA.

Comment:
The tumour stains as follow:
POSITIVE: TTF-1, CK5/6 (focal), p63, napsin A.
NEGATIVE: (none).

The positive staining (TTF-1 and napsin A versus CK5/6 and p63) appears to be in different tumour cells.  

The case was reviewed internally and there is agreement on the above interpretation.

Note:

  • Cases should not be signed as adenosquamous carcinoma on biopsy, due to the percentage requirements of the diagnosis.

See also

References

  1. ↑ Song, Z.; Lin, B.; Shao, L.; Zhang, Y. (Sep 2013). "Therapeutic efficacy of gefitinib and erlotinib in patients with advanced lung adenosquamous carcinoma.". J Chin Med Assoc 76 (9): 481-5. doi:10.1016/j.jcma.2013.05.007. PMID 23769878.
  2. ↑ Iwanaga, K.; Sueoka-Aragane, N.; Nakamura, T.; Mori, D.; Kimura, S. (2012). "The long-term survival of a patient with adenosquamous lung carcinoma harboring EGFR-activating mutations who was treated with gefitinib.". Intern Med 51 (19): 2771-4. PMID 23037472.
Retrieved from "https://librepathology.org/w/index.php?title=Adenosquamous_carcinoma_of_the_lung&oldid=48462"