Difference between revisions of "Intestinal spirochetosis"

From Libre Pathology
Jump to navigation Jump to search
Line 64: Line 64:


===Images===
===Images===
*[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830567/figure/F3/  
*[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830567/figure/F3/ Spirochetes shown with a Warthin-Starry stain (nih.gov)].<ref name=pmid20200654>{{Cite journal  | last1 = Tsinganou | first1 = E. | last2 = Gebbers | first2 = JO. | title = Human intestinal spirochetosis--a review. | journal = Ger Med Sci | volume = 8 | issue =  | pages = Doc01 | month = Jan | year = 2010 | doi = 10.3205/000090 | PMID = 20200654 }}</ref>
Spirochetes shown with a Warthin-Starry stain (nih.gov)].<ref name=pmid20200654>{{Cite journal  | last1 = Tsinganou | first1 = E. | last2 = Gebbers | first2 = JO. | title = Human intestinal spirochetosis--a review. | journal = Ger Med Sci | volume = 8 | issue =  | pages = Doc01 | month = Jan | year = 2010 | doi = 10.3205/000090 | PMID = 20200654 }}</ref>


==See also==
==See also==

Revision as of 18:20, 19 October 2017

Intestinal spirochetosis
Diagnosis in short

Intestinal spirochetosis. H&E stain.
LM hyperchromatic fuzz on luminal aspect of epithelial cells - at brush border; spirochetes
Stains silver stains, e.g. Warthin-Starry stain
Site intestine - colon
Signs watery diarrhea +/-blood per rectum
Symptoms abdominal pain
Prevalence uncommon
Prognosis benign
Clin. DDx other causes of diarrhea
Treatment antibiotics

Intestinal spirochetosis, also known as intestinal spirochetes, in an uncommon intestinal infection.

It is usually in the colon; thus, also known as colonic spirochetes and colonic spirochetosis.

General

  • Caused by spirochetes[1][2] - specifically Brachyspira piloicoli[3] (previously Serpulina pilosicoli[4]) and Brachyspira aalborgi.
  • Very rare cause of diarrhea, associated with male homosexual behaviour.

Symptoms:[2]

  • Watery diarrhea, abdominal pain, +/-blood per rectum.

Treatment:[5]

  • Metronidazole.

Microscopic

Features:

  • Hyperchromatic fuzz on luminal aspect of epithelial cells; at brush border.

DDx:

Images

  • Intestinal spirochetes - cropped - very high mag. (WC/Nephron)

  • Intestinal spirochetes - very high mag. (WC/Nephron)

  • Intestinal spirochetes - intermed. mag. (WC/Nephron)

www:

Special stains

Images

See also

References

  1. ↑ Amat Villegas I, Borobio Aguilar E, Beloqui Perez R, de Llano Varela P, Oquiñena Legaz S, Martínez-Peñuela Virseda JM (January 2004). "[Colonic spirochetes: an infrequent cause of adult diarrhea]" (in Spanish; Castilian). Gastroenterol Hepatol 27 (1): 21–3. PMID 14718105.
  2. ↑ 2.0 2.1 URL: http://www.jhasim.com/files/articlefiles/pdf/XASIM_Master_6_5_May_Vignette.pdf. Accessed on: 25 April 2011.
  3. ↑ Margawani, KR.; Robertson, ID.; Hampson, DJ. (Feb 2009). "Isolation of the anaerobic intestinal spirochaete Brachyspira pilosicoli from long-term residents and Indonesian visitors to Perth, Western Australia.". J Med Microbiol 58 (Pt 2): 248-52. doi:10.1099/jmm.0.004770-0. PMID 19141744. http://ukpmc.ac.uk/abstract/MED/19141744/abstract/MED/19141744?ukpmc_extredirect=http://dx.doi.org/10.1099/jmm.0.004770-0.
  4. ↑ URL: http://www.cdc.gov/ncidod/eid/vol12no05/05-1180.htm. Accessed on: 28 June 2011.
  5. ↑ Calderaro A, Bommezzadri S, Gorrini C, et al. (November 2007). "Infective colitis associated with human intestinal spirochetosis". J. Gastroenterol. Hepatol. 22 (11): 1772–9. doi:10.1111/j.1440-1746.2006.04606.x. PMID 17914949.
  6. ↑ Tsinganou, E.; Gebbers, JO. (Jan 2010). "Human intestinal spirochetosis--a review.". Ger Med Sci 8: Doc01. doi:10.3205/000090. PMID 20200654.
Retrieved from "https://librepathology.org/w/index.php?title=Intestinal_spirochetosis&oldid=48074"