Difference between revisions of "Small bowel pseudomelanosis"
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*[[Hypertension]] ~90% of cases. | *[[Hypertension]] ~90% of cases. | ||
*Iron supplementation ~75% of cases. | *Iron supplementation ~75% of cases. | ||
*End-stage renal disease ~60% of cases. | *[[End-stage renal disease]] ~60% of cases. | ||
Note: | Note: | ||
Revision as of 22:26, 8 March 2016
Pseudomelanosis duodeni is benign change of the duodenum that mimics melanin deposition.
General
- Rare.
- Consists of iron and lipofuscin.[1]
Associations:[2]
- Hypertension ~90% of cases.
- Iron supplementation ~75% of cases.
- End-stage renal disease ~60% of cases.
Note:
- The associations are different than for melanosis coli.
Gross/endoscopic
- Dark spots ~35% of cases.[2]
Microscopic
Features:
- Dark pigment in the lamina propria macrophages.
Images:
Stains
- Prussian blue +ve ~80% of cases.[2]
See also
References
- ↑ Lin, HJ.; Tsay, SH.; Chiang, H.; Tsai, YT.; Lee, SD.; Yeh, YS.; Lo, GH. (Apr 1988). "Pseudomelanosis duodeni. Case report and review of literature.". J Clin Gastroenterol 10 (2): 155-9. PMID 2458404.
- ↑ 2.0 2.1 2.2 Giusto, D.; Jakate, S. (Feb 2008). "Pseudomelanosis duodeni: associated with multiple clinical conditions and unpredictable iron stainability - a case series.". Endoscopy 40 (2): 165-7. doi:10.1055/s-2007-995472. PMID 18253910.