Difference between revisions of "S-100"
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'''S-100''', also '''S100''', is a commonly used [[immunostain]]. It marks nerves. | '''S-100''', also '''S100''', is a commonly used [[immunostain]]. It marks nerves. | ||
<!-- Dabbs' IHC book uses 'S-100' --> | <!-- Dabbs' IHC book uses 'S-100' as opposed to 'S100' --> | ||
==Positive== | ==Positive== | ||
*Nerves. | *Nerves. | ||
*Interdigitating dendritic cells.<ref>{{Cite journal | last1 = Mesquita | first1 = RA. | last2 = de Araújo | first2 = VC. | last3 = Paes | first3 = RA. | last4 = Nunes | first4 = FD. | last5 = de Souza | first5 = SC. | title = Immunohistochemical analysis for CD21, CD35, Caldesmon and S100 protein on dendritic cells types in oral lymphomas. | journal = J Appl Oral Sci | volume = 17 | issue = 3 | pages = 248-53 | month = | year = | doi = | PMID = 19466261 }} | *Mature adipose tissue. | ||
*Interdigitating dendritic cells.<ref name=pmid19466261>{{Cite journal | last1 = Mesquita | first1 = RA. | last2 = de Araújo | first2 = VC. | last3 = Paes | first3 = RA. | last4 = Nunes | first4 = FD. | last5 = de Souza | first5 = SC. | title = Immunohistochemical analysis for CD21, CD35, Caldesmon and S100 protein on dendritic cells types in oral lymphomas. | journal = J Appl Oral Sci | volume = 17 | issue = 3 | pages = 248-53 | month = | year = | doi = | PMID = 19466261 }} | |||
</ref> | </ref> | ||
*[[Langerhans cell histiocytosis]]. | *[[Langerhans cell histiocytosis]]. |
Revision as of 16:05, 4 November 2015
S-100, also S100, is a commonly used immunostain. It marks nerves.
Positive
- Nerves.
- Mature adipose tissue.
- Interdigitating dendritic cells.[1]
- Langerhans cell histiocytosis.
- Rosai-Dorfman disease.
- Malignant melanoma - almost 100% sensitive.