Difference between revisions of "Renal angiomyoadenomatous tumour"
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==Microscopic== | ==Microscopic== | ||
Features:<ref name=pmid22534244>{{Cite journal | last1 = Singh | first1 = C. | last2 = Kendi | first2 = AT. | last3 = Manivel | first3 = JC. | last4 = Pambuccian | first4 = SE. | title = Renal angiomyoadenomatous tumor. | journal = Ann Diagn Pathol | volume = 16 | issue = 6 | pages = 470-6 | month = Dec | year = 2012 | doi = 10.1016/j.anndiagpath.2012.01.006 | PMID = 22534244 }}</ref> | Features:<ref name=pmid22534244>{{Cite journal | last1 = Singh | first1 = C. | last2 = Kendi | first2 = AT. | last3 = Manivel | first3 = JC. | last4 = Pambuccian | first4 = SE. | title = Renal angiomyoadenomatous tumor. | journal = Ann Diagn Pathol | volume = 16 | issue = 6 | pages = 470-6 | month = Dec | year = 2012 | doi = 10.1016/j.anndiagpath.2012.01.006 | PMID = 22534244 }}</ref><ref name=pmid19020896>{{Cite journal | last1 = Michal | first1 = M. | last2 = Hes | first2 = O. | last3 = Nemcova | first3 = J. | last4 = Sima | first4 = R. | last5 = Kuroda | first5 = N. | last6 = Bulimbasic | first6 = S. | last7 = Franco | first7 = M. | last8 = Sakaida | first8 = N. | last9 = Danis | first9 = D. | title = Renal angiomyoadenomatous tumor: morphologic, immunohistochemical, and molecular genetic study of a distinct entity. | journal = Virchows Arch | volume = 454 | issue = 1 | pages = 89-99 | month = Jan | year = 2009 | doi = 10.1007/s00428-008-0697-3 | PMID = 19020896 }}</ref> | ||
*Leiomyomatous capsule of variable thickness - '''key feature'''. | *Leiomyomatous capsule of variable thickness - '''key feature'''. | ||
*Clear cells with basal nuclei and mild [[nuclear atypia]]. | *Tubular structures with: | ||
**Apical snouts. | |||
**Clear cells with basal nuclei and mild [[nuclear atypia]]. | |||
DDx:<ref name=pmid22534244/><ref>{{Cite journal | last1 = Petersson | first1 = F. | last2 = Branzovsky | first2 = J. | last3 = Martinek | first3 = P. | last4 = Korabecna | first4 = M. | last5 = Kruslin | first5 = B. | last6 = Hora | first6 = M. | last7 = Peckova | first7 = K. | last8 = Bauleth | first8 = K. | last9 = Pivovarcikova | first9 = K. | title = The leiomyomatous stroma in renal cell carcinomas is polyclonal and not part of the neoplastic process. | journal = Virchows Arch | volume = 465 | issue = 1 | pages = 89-96 | month = Jul | year = 2014 | doi = 10.1007/s00428-014-1591-9 | PMID = 24838683 }}</ref> | DDx:<ref name=pmid22534244/><ref>{{Cite journal | last1 = Petersson | first1 = F. | last2 = Branzovsky | first2 = J. | last3 = Martinek | first3 = P. | last4 = Korabecna | first4 = M. | last5 = Kruslin | first5 = B. | last6 = Hora | first6 = M. | last7 = Peckova | first7 = K. | last8 = Bauleth | first8 = K. | last9 = Pivovarcikova | first9 = K. | title = The leiomyomatous stroma in renal cell carcinomas is polyclonal and not part of the neoplastic process. | journal = Virchows Arch | volume = 465 | issue = 1 | pages = 89-96 | month = Jul | year = 2014 | doi = 10.1007/s00428-014-1591-9 | PMID = 24838683 }}</ref> | ||
Revision as of 02:27, 21 October 2014
Renal angiomyoadenomatous tumour, abbreviated RAT, is an uncommon kidney tumour not recognized by the WHO classification of renal neoplasia or the Vancouver modification.
General
- May be on a spectrum with clear cell papillary renal cell carcinoma.[1]
Clincal:
- Usually middle age (40s and 50s).
Gross
Features:[2]
- Tan-brown renal mass +/-cystic component.
Microscopic
- Leiomyomatous capsule of variable thickness - key feature.
- Tubular structures with:
- Apical snouts.
- Clear cells with basal nuclei and mild nuclear atypia.
- Clear cell renal cell carcinoma.
- Papillary renal cell carcinoma.
- Angiomyolipoma.
- Mixed epithelial and stromal tumour of the kidney.
See also
References
- ↑ Petersson, F.; Grossmann, P.; Hora, M.; Sperga, M.; Montiel, DP.; Martinek, P.; Gutierrez, ME.; Bulimbasic, S. et al. (Jul 2013). "Renal cell carcinoma with areas mimicking renal angiomyoadenomatous tumor/clear cell papillary renal cell carcinoma.". Hum Pathol 44 (7): 1412-20. doi:10.1016/j.humpath.2012.11.019. PMID 23434146.
- ↑ 2.0 2.1 2.2 Singh, C.; Kendi, AT.; Manivel, JC.; Pambuccian, SE. (Dec 2012). "Renal angiomyoadenomatous tumor.". Ann Diagn Pathol 16 (6): 470-6. doi:10.1016/j.anndiagpath.2012.01.006. PMID 22534244.
- ↑ Michal, M.; Hes, O.; Nemcova, J.; Sima, R.; Kuroda, N.; Bulimbasic, S.; Franco, M.; Sakaida, N. et al. (Jan 2009). "Renal angiomyoadenomatous tumor: morphologic, immunohistochemical, and molecular genetic study of a distinct entity.". Virchows Arch 454 (1): 89-99. doi:10.1007/s00428-008-0697-3. PMID 19020896.
- ↑ Petersson, F.; Branzovsky, J.; Martinek, P.; Korabecna, M.; Kruslin, B.; Hora, M.; Peckova, K.; Bauleth, K. et al. (Jul 2014). "The leiomyomatous stroma in renal cell carcinomas is polyclonal and not part of the neoplastic process.". Virchows Arch 465 (1): 89-96. doi:10.1007/s00428-014-1591-9. PMID 24838683.