Difference between revisions of "Angiokeratoma"
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Angiokeratoma_-_intermed_mag.jpg | |||
| Width = | |||
| Caption = Angiokeratoma. [[H&E stain]]. | |||
| Synonyms = | |||
| Micro = ectatic superficial dermal vessels with overlying hyperkeratosis (thick stratum corneum); should have "epidermal collarette" (vascular space is surrounded by epidermis on three sides) | |||
| Subtypes = | |||
| LMDDx = [[venous lake]] | |||
| Stains = | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[skin]] | |||
| Assdx = | |||
| Syndromes = [[Fabry disease]] | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = uncommon | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = benign | |||
| Other = | |||
| ClinDDx = [[melanocytic lesions]], other [[vascular lesions]] | |||
| Tx = | |||
}} | |||
'''Angiokeratoma''' is a benign [[skin]] lesion. | '''Angiokeratoma''' is a benign [[skin]] lesion. | ||
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Image:Angiokeratoma_-_low_mag.jpg | Angiokeratoma - low mag. (WC/Nephron) | Image:Angiokeratoma_-_low_mag.jpg | Angiokeratoma - low mag. (WC/Nephron) | ||
Image:Angiokeratoma_-_intermed_mag.jpg | Angiokeratoma - intermed. mag. (WC/Nephron) | Image:Angiokeratoma_-_intermed_mag.jpg | Angiokeratoma - intermed. mag. (WC/Nephron) | ||
Image:Angiokeratoma_-_high_mag.jpg | Angiokeratoma - high mag. (WC/Nephron) | |||
</gallery> | </gallery> | ||
www: | www: | ||
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{{Reflist|2}} | {{Reflist|2}} | ||
[[Category: | [[Category:Non-malignant skin disease]] | ||
[[Category:Diagnosis]] | [[Category:Diagnosis]] |
Revision as of 01:47, 20 June 2014
Angiokeratoma | |
---|---|
Diagnosis in short | |
Angiokeratoma. H&E stain. | |
| |
LM | ectatic superficial dermal vessels with overlying hyperkeratosis (thick stratum corneum); should have "epidermal collarette" (vascular space is surrounded by epidermis on three sides) |
LM DDx | venous lake |
Site | skin |
| |
Syndromes | Fabry disease |
| |
Prevalence | uncommon |
Prognosis | benign |
Clin. DDx | melanocytic lesions, other vascular lesions |
Angiokeratoma is a benign skin lesion.
General
- Rare.
- May be seen in the context of Fabry disease.[1]
Notes:
- Shouldn't be confused with angiofibroma which is associated tuberous sclerosis.
Gross
- Dark lesions.
Clinical DDx:
Images
Microscopic
Features:[1]
- Ectatic superficial dermal vessels.
- Overlying hyperkeratosis (thick stratum corneum).
- Should have "epidermal collarette".[2]
- Vascular space surrounded by epidermis on three sides.
Others features:[citation needed]
- Irregular acanthosis.
- Longer rete ridges.
DDx:
Images
www:
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SKIN LESION, LEFT POPITEAL FOSSA, PUNCH BIOPSY: - ANGIOKERATOMA.