Difference between revisions of "Granular cell tumour"
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Features: | Features: | ||
*Abundant eosinophilic granular cytoplasm. | *Abundant eosinophilic granular cytoplasm. | ||
**Granules 1-3 micrometers | **Granules: | ||
***Size: 1-3 micrometers. | |||
***Poorly demarcated. | |||
==Special stains== | ==Special stains== | ||
Revision as of 05:48, 19 November 2010
The granular cell tumour is a rare beast.
General
- Rare.
- Usually benign.
Gross
- Yellow nodule.
Note:
- DDx of yellow nodule: granular cell tumour, lipoma, xanthoma.
Microscopic
Features:
- Abundant eosinophilic granular cytoplasm.
- Granules:
- Size: 1-3 micrometers.
- Poorly demarcated.
- Granules:
Special stains
- PAS +ve.
IHC
Features:[1]
- S100 +ve.
- CD68 +ve (cytoplasmic).
- Vimentin +ve (membranous).
Images:
_skin.jpg){kind=link}
_S-100.JPG){kind=link}
See also
References
- ↑ Rekhi, B.; Jambhekar, NA. (Jun 2010). "Morphologic spectrum, immunohistochemical analysis, and clinical features of a series of granular cell tumors of soft tissues: a study from a tertiary referral cancer center.". Ann Diagn Pathol 14 (3): 162-7. doi:10.1016/j.anndiagpath.2010.01.005. PMID 20471560.