Difference between revisions of "Gastric xanthoma"
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'''Gastric xanthoma''', abbreviated ''GX'', is an uncommon benign lesion of the stomach. | |||
It is also known as '''xanthelasma''' and '''stomach lipidosis'''. | |||
==General== | |||
*Uncommon. | |||
*Benign. | |||
==Gross/endoscopic== | |||
*Yellowish nodule or plaque.<ref name=Ref_GLP111>{{Ref GLP|111}}</ref> | |||
**Classically lesser curvature and antrum.<ref name=pmid6284833/> | |||
==Microscopic== | |||
Features:<ref name=Ref_GLP111>{{Ref GLP|111}}</ref> | |||
*Collections of gastric lamina propria with lipid-laden macrophages. | |||
DDx: | |||
*[[Signet ring cell carcinoma]].<ref name=pmid6284833>{{Cite journal | last1 = Drude | first1 = RB. | last2 = Balart | first2 = LA. | last3 = Herrington | first3 = JP. | last4 = Beckman | first4 = EN. | last5 = Burns | first5 = TW. | title = Gastric xanthoma: histologic similarity to signet ring cell carcinoma. | journal = J Clin Gastroenterol | volume = 4 | issue = 3 | pages = 217-21 | month = Jun | year = 1982 | doi = | PMID = 6284833 }}</ref> | |||
*[[Whipple disease]]. | |||
*MAC infection. | |||
===Images=== | |||
<gallery> | |||
image:Xanthoma_histology.jpg | Xanthoma. (WC) | |||
</gallery> | |||
www: | |||
*[http://www.flickr.com/photos/hemeguy/2911032670/in/photostream/ GX - low mag. (flickr.com)]. | |||
*[http://www.flickr.com/photos/hemeguy/2911031464/in/photostream GX - high mag. (flickr.com)]. | |||
==IHC== | |||
*CD68 +ve. | |||
*Panker (AE1/AE3) -ve. | |||
**To exclude carcinoma. | |||
==See also== | |||
*[[Stomach]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Stomach]] | |||
Revision as of 04:01, 22 December 2013
Gastric xanthoma, abbreviated GX, is an uncommon benign lesion of the stomach.
It is also known as xanthelasma and stomach lipidosis.
General
- Uncommon.
- Benign.
Gross/endoscopic
Microscopic
Features:[1]
- Collections of gastric lamina propria with lipid-laden macrophages.
DDx:
- Signet ring cell carcinoma.[2]
- Whipple disease.
- MAC infection.
Images
Xanthoma. (WC)
www:
IHC
- CD68 +ve.
- Panker (AE1/AE3) -ve.
- To exclude carcinoma.
See also
References
- ↑ 1.0 1.1 Iacobuzio-Donahue, Christine A.; Montgomery, Elizabeth A. (2005). Gastrointestinal and Liver Pathology: A Volume in the Foundations in Diagnostic Pathology Series (1st ed.). Churchill Livingstone. pp. 111. ISBN 978-0443066573.
- ↑ 2.0 2.1 Drude, RB.; Balart, LA.; Herrington, JP.; Beckman, EN.; Burns, TW. (Jun 1982). "Gastric xanthoma: histologic similarity to signet ring cell carcinoma.". J Clin Gastroenterol 4 (3): 217-21. PMID 6284833.