Difference between revisions of "Intestinal metaplasia of the gallbladder"

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==General==
==General==
Significance:
Significance:
*Increased risk of carcinoma.<ref name=pmid8364865/>
*Increased risk of carcinoma.<ref name=pmid8364865>{{Cite journal  | last1 = Duarte | first1 = I. | last2 = Llanos | first2 = O. | last3 = Domke | first3 = H. | last4 = Harz | first4 = C. | last5 = Valdivieso | first5 = V. | title = Metaplasia and precursor lesions of gallbladder carcinoma. Frequency, distribution, and probability of detection in routine histologic samples. | journal = Cancer | volume = 72 | issue = 6 | pages = 1878-84 | month = Sep | year = 1993 | doi =  | PMID = 8364865 }}</ref>


==Gross==
==Gross==

Revision as of 02:01, 15 December 2013

Intestinal metaplasia of the gallbladder
Diagnosis in short

Gallbladder with intestinal metaplasia. H&E stain.
LM DDx gallbladder mucosa with goblet cells
Stains Alcian blue stain +ve
Site gallbladder
Associated Dx chronic cholecystitis
Prognosis benign, increased risk of carcinoma

Intestinal metaplasia of the gallbladder is a pathology of the gallbladder associated with an increased risk of gallbladder carcinoma.

It is also known as gallbladder intestinal metaplasia.

General

Significance:

  • Increased risk of carcinoma.[1]

Gross

  • No specific changes.

Microscopic

Features:[2]

Note:

  • Often accompanied by antral type metplasia.
    • Gastric antral-type epithelium - may form glands.

DDx:

Images

  • GB with IM - low mag.

  • GB with IM - intermed. mag.

  • GB with IM - high mag.

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GALLBLADDER, CHOLECYSTECTOMY: 
- INTESTINAL METAPLASIA OF THE GALLBLADDER, FOCAL. 
- CHRONIC CHOLECYSTITIS. 
- CHOLELITHIASIS.
- NEGATIVE FOR DYSPLASIA.

See also

References

  1. ↑ Duarte, I.; Llanos, O.; Domke, H.; Harz, C.; Valdivieso, V. (Sep 1993). "Metaplasia and precursor lesions of gallbladder carcinoma. Frequency, distribution, and probability of detection in routine histologic samples.". Cancer 72 (6): 1878-84. PMID 8364865.
  2. ↑ Albores-Saavedra, J.; Nadji, M.; Henson, DE.; Ziegels-Weissman, J.; Mones, JM. (Jun 1986). "Intestinal metaplasia of the gallbladder: a morphologic and immunocytochemical study.". Hum Pathol 17 (6): 614-20. PMID 2872152.
  3. ↑ Mills, Stacey E; Carter, Darryl; Greenson, Joel K; Oberman, Harold A; Reuter, Victor E (2004). Sternberg's Diagnostic Surgical Pathology (4th ed.). Lippincott Williams & Wilkins. pp. 1789. ISBN 978-0781740517.
  4. ↑ Cite error: Invalid <ref> tag; no text was provided for refs named pmid15737036
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