Difference between revisions of "Intestinal metaplasia of the gallbladder"

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#redirect [[Gallbladder#Intestinal_metaplasia_of_the_gallbladder]]
{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Image      = Gallbladder with intestinal metaplasia -- intermed mag.jpg
| Width      =
| Caption    = Gallbladder with intestinal metaplasia. [[H&E stain]].
| Micro      =
| Subtypes  =
| LMDDx      = gallbladder mucosa with goblet cells
| Stains    = [[Alcian blue stain]] +ve
| IHC        =
| EM        =
| Molecular  =
| IF        =
| Gross      =
| Grossing  =
| Site      = [[gallbladder]]
| Assdx      = [[chronic cholecystitis]]
| Syndromes  =
| Clinicalhx =
| Signs      =
| Symptoms  =
| Prevalence =
| Bloodwork  =
| Rads      =
| Endoscopy  =
| Prognosis  = benign, increased risk of carcinoma
| Other      =
| ClinDDx    =
}}
'''Intestinal metaplasia of the gallbladder''' is a pathology of the gallbladder associated with an increased risk of [[gallbladder carcinoma]].
 
It is also known as '''gallbladder [[intestinal metaplasia]]'''.
==General==
Significance:
*Increased risk of carcinoma.<ref name=pmid8364865/>
 
==Gross==
*No specific changes.
 
==Microscopic==
Features:<ref name=pmid2872152>{{Cite journal  | last1 = Albores-Saavedra | first1 = J. | last2 = Nadji | first2 = M. | last3 = Henson | first3 = DE. | last4 = Ziegels-Weissman | first4 = J. | last5 = Mones | first5 = JM. | title = Intestinal metaplasia of the gallbladder: a morphologic and immunocytochemical study. | journal = Hum Pathol | volume = 17 | issue = 6 | pages = 614-20 | month = Jun | year = 1986 | doi =  | PMID = 2872152 }}</ref>
*[[Goblet cell]]s - '''key feature'''.
*+/-Paneth cells.<ref name=Ref_Sternberg4_1789>{{Ref Sternberg4|1789}}</ref>
 
Note:
*Often accompanied by antral type metplasia.
**Gastric antral-type epithelium - may form glands.
 
DDx:
*[[Gallbladder adenocarcinoma]].
 
===Images===
<gallery>
Image: Gallbladder with intestinal metaplasia -- low mag.jpg | GB with IM - low mag.
Image: Gallbladder with intestinal metaplasia -- intermed mag.jpg | GB with IM - intermed. mag.
Image: Gallbladder with intestinal metaplasia -- high mag.jpg | GB with IM - high mag.
</gallery>
www:
*[http://www.archivesofpathology.org/action/showFullPopup?id=i1543-2165-129-3-386-f01&doi=10.1043%2F1543-2165%282005%29129%3C386%3APPOGDA%3E2.0.CO%3B2 IM - among other things (archivesofpathology.org)].<ref name=pmid15737036/>
 
==Sign out==
<pre>
GALLBLADDER, CHOLECYSTECTOMY:
- INTESTINAL METAPLASIA OF THE GALLBLADDER, FOCAL.
- CHRONIC CHOLECYSTITIS.
- CHOLELITHIASIS.
- NEGATIVE FOR DYSPLASIA.
</pre>
 
==See also==
*[[Gallbladder]].
*[[Intestinal metaplasia]].
 
==References==
{{Reflist|2}}


[[Category:Diagnosis]]
[[Category:Diagnosis]]
[[Category:Gallbladder]]

Revision as of 01:48, 15 December 2013

Intestinal metaplasia of the gallbladder
Diagnosis in short

Gallbladder with intestinal metaplasia. H&E stain.
LM DDx gallbladder mucosa with goblet cells
Stains Alcian blue stain +ve
Site gallbladder
Associated Dx chronic cholecystitis
Prognosis benign, increased risk of carcinoma

Intestinal metaplasia of the gallbladder is a pathology of the gallbladder associated with an increased risk of gallbladder carcinoma.

It is also known as gallbladder intestinal metaplasia.

General

Significance:

  • Increased risk of carcinoma.[1]

Gross

  • No specific changes.

Microscopic

Features:[2]

Note:

  • Often accompanied by antral type metplasia.
    • Gastric antral-type epithelium - may form glands.

DDx:

Images

  • GB with IM - low mag.

  • GB with IM - intermed. mag.

  • GB with IM - high mag.

www:

Sign out

GALLBLADDER, CHOLECYSTECTOMY: 
- INTESTINAL METAPLASIA OF THE GALLBLADDER, FOCAL. 
- CHRONIC CHOLECYSTITIS. 
- CHOLELITHIASIS.
- NEGATIVE FOR DYSPLASIA.

See also

References

  1. ↑ Cite error: Invalid <ref> tag; no text was provided for refs named pmid8364865
  2. ↑ Albores-Saavedra, J.; Nadji, M.; Henson, DE.; Ziegels-Weissman, J.; Mones, JM. (Jun 1986). "Intestinal metaplasia of the gallbladder: a morphologic and immunocytochemical study.". Hum Pathol 17 (6): 614-20. PMID 2872152.
  3. ↑ Mills, Stacey E; Carter, Darryl; Greenson, Joel K; Oberman, Harold A; Reuter, Victor E (2004). Sternberg's Diagnostic Surgical Pathology (4th ed.). Lippincott Williams & Wilkins. pp. 1789. ISBN 978-0781740517.
  4. ↑ Cite error: Invalid <ref> tag; no text was provided for refs named pmid15737036
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