Difference between revisions of "Fibroepithelial polyp"

Fibroepithelial polyp
	Diagnosis in short
	; Fibroepithelial polyp. H&E stain.
LM	On a stalk / epithelium on three sides, benign epidermis, fibrous core, +/-inflammation
LM DDx	Regressing melanocytic lesions (esp. intradermal melanocytic nevus), pedunculated seborrheic keratosis, nevus lipomatosus superficialis, neurofibroma
Gross	raised skin-coloured lesion
Site	skin
Prevalence	very common
Prognosis	benign

Revision as of 01:50, 14 October 2013

Fibroepithelial polyp, also known as acrochordon and skin tag, is a very common benign skin lesion.

General

Benign.
Older people.
May be associated with pregnancy, diabetes, intestinal polyposis.^[1]
Can be a component of Birt–Hogg–Dubé syndrome.

Gross

Raised skin-coloured lesion.

Image:

Skin tag (WC).

Microscopic

Features:

On a stalk / epithelium on three sides.
Benign epidermis.
Fibrous core.
+/-Inflammation.

DDx:

Pedunculated seborrheic keratosis - typically have epidermal hyperplasia, hyperkeratosis, horn cysts.^[2]
Regressing melanocytic lesions.
- Intradermal melanocytic nevus.
Nevus lipomatosus superficialis - abundant adipocytes in the superficial dermis.
Neurofibroma.

Images

Skin tag. (WC)

www:

Sign out

EYELID ("TAG"), RIGHT, REMOVAL:
- BENIGN FIBROEPITHELIAL POLYP.

SKIN ("SKIN TAG"), THIGH, REMOVAL:
- FIBROEPITHELIAL POLYP.

Micro

The sections show a fragment of skin with epithelium on three sides. The epithelium matures normally and is not hypertrophic. Orthokeratosis is present. The core of the lesion has fibrous tissue. There is no significant inflammation. No melanocytic nests are identified.

Inflamed

The sections show a fragment of skin with epithelium on three sides. The epithelium matures and is acanthotic. Minimal parakeratosis is present. The core of the lesion consists of fibrous tissue with a mild lymphocyte-predominant dermal infiltrate. Rare siderophages are present.

There is mild basal nuclear enlargement. No significant nuclear atypia is apparent. The dermal-epidermal interface is well-demarcated. Rare basal mitotic activity is identified.

References

↑ Mitchell, Richard; Kumar, Vinay; Fausto, Nelson; Abbas, Abul K.; Aster, Jon (2011). Pocket Companion to Robbins & Cotran Pathologic Basis of Disease (8th ed.). Elsevier Saunders. pp. 596. ISBN 978-1416054542.
↑ Busam, Klaus J. (2009). Dermatopathology: A Volume in the Foundations in Diagnostic Pathology Series (1st ed.). Saunders. pp. 342. ISBN 978-0443066542.
↑ URL: http://dermatlas.med.jhmi.edu/derm/result.cfm?Diagnosis=1196583692. Accessed on: 1 September 2011.
↑ URL: http://dermatology-s10.cdlib.org/143/case_presentations/skintags/allegue.html. Accessed on: 9 January 2013.

[Ref_PCPBoD8.7C596-1] Mitchell, Richard; Kumar, Vinay; Fausto, Nelson; Abbas, Abul K.; Aster, Jon (2011). Pocket Companion to Robbins & Cotran Pathologic Basis of Disease (8th ed.). Elsevier Saunders. pp. 596. ISBN 978-1416054542.

[Ref_Derm342-2] Busam, Klaus J. (2009). Dermatopathology: A Volume in the Foundations in Diagnostic Pathology Series (1st ed.). Saunders. pp. 342. ISBN 978-0443066542.

[3] URL: http://dermatlas.med.jhmi.edu/derm/result.cfm?Diagnosis=1196583692. Accessed on: 1 September 2011.

[4] URL: http://dermatology-s10.cdlib.org/143/case_presentations/skintags/allegue.html. Accessed on: 9 January 2013.

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[2]

[3]

[4]

@@ Line 1: / Line 1: @@
-#redirect [[Non-malignant_skin_disease#Fibroepithelial_polyp]]
+{{ Infobox diagnosis
+| Name       = {{PAGENAME}}
+| Image      = SkinTumors-P9250819.jpg
+| Width      =
+| Caption    = Fibroepithelial polyp. [[H&E stain]].
+| Micro      = On a stalk / epithelium on three sides, benign epidermis, fibrous core, +/-inflammation
+| Subtypes   =
+| LMDDx      = Regressing [[melanocytic lesions]] (esp. [[intradermal melanocytic nevus]]), pedunculated [[seborrheic keratosis]], [[nevus lipomatosus superficialis]], [[neurofibroma]]
+| Stains     =
+| IHC        =
+| EM         =
+| Molecular  =
+| IF         =
+| Gross      = raised skin-coloured lesion
+| Grossing   =
+| Site       = [[skin]]
+| Assdx      =
+| Syndromes  =
+| Clinicalhx =
+| Signs      =
+| Symptoms   =
+| Prevalence = very common
+| Bloodwork  =
+| Rads       =
+| Endoscopy  =
+| Prognosis  = benign
+| Other      =
+| ClinDDx    =
+}}
+'''Fibroepithelial polyp''', also known as '''acrochordon''' and '''skin tag''', is a very common benign skin lesion.
+==General==
+*Benign.
+*Older people.
+*May be associated with pregnancy, [[diabetes]], [[intestinal polyposis]].<ref name=Ref_PCPBoD8|596>{{Ref PCPBoD8|596}}</ref>
+*Can be a component of ''[[Birt–Hogg–Dubé syndrome]]''.
+==Gross==
+*Raised skin-coloured lesion.
+Image:
+*[http://commons.wikimedia.org/wiki/File:Skintagblemish.jpg Skin tag (WC)].
+==Microscopic==
+Features:
+*On a stalk / epithelium on three sides.
+*Benign epidermis.
+*Fibrous core.
+*+/-Inflammation.
+DDx:
+*Pedunculated [[seborrheic keratosis]] - typically have epidermal hyperplasia, hyperkeratosis, horn cysts.<ref name=Ref_Derm342>{{Ref Derm|342}}</ref>
+*Regressing [[melanocytic lesions]].
+**[[Intradermal melanocytic nevus]].
+*[[Nevus lipomatosus superficialis]] - abundant adipocytes in the superficial dermis.
+*[[Neurofibroma]].
+===Images===
+<gallery>
+Image:SkinTumors-P9250819.jpg | Skin tag. (WC)
+</gallery>
+www:
+*[http://dermatlas.med.jhmi.edu/derm/IndexDisplay.cfm?ImageID=1767547949 Fibroepithelial polyp (dermatlas.med.jhmi.edu)].<ref>URL: [http://dermatlas.med.jhmi.edu/derm/result.cfm?Diagnosis=1196583692 http://dermatlas.med.jhmi.edu/derm/result.cfm?Diagnosis=1196583692]. Accessed on: 1 September 2011.</ref>
+*[http://www.surgicalpathologyatlas.com/glfusion/mediagallery/media.php?f=0&sort=0&s=20080802171929218 Fibroepithelial polyp (surgicalpathologyatlas.com)].
+*[http://dermatology-s10.cdlib.org/143/case_presentations/skintags/3.jpg Inflamed fibroepithelial polyp (cdlib.org)].<ref>URL: [http://dermatology-s10.cdlib.org/143/case_presentations/skintags/allegue.html http://dermatology-s10.cdlib.org/143/case_presentations/skintags/allegue.html]. Accessed on: 9 January 2013.</ref>
+==Sign out==
+<pre>
+EYELID ("TAG"), RIGHT, REMOVAL:
+- BENIGN FIBROEPITHELIAL POLYP.
+</pre>
+<pre>
+SKIN ("SKIN TAG"), THIGH, REMOVAL:
+- FIBROEPITHELIAL POLYP.
+</pre>
+===Micro===
+The sections show a fragment of skin with epithelium on three sides.  The epithelium matures normally and is not hypertrophic.  Orthokeratosis is present. The core of the lesion has fibrous tissue.  There is no significant inflammation. No melanocytic nests are identified.
+====Inflamed====
+The sections show a fragment of skin with epithelium on three sides. The epithelium matures
+and is acanthotic. Minimal parakeratosis is present. The core of the lesion consists of
+fibrous tissue with a mild lymphocyte-predominant dermal infiltrate.  Rare siderophages are
+present.
+There is mild basal nuclear enlargement.  No significant nuclear atypia is apparent. The
+dermal-epidermal interface is well-demarcated. Rare basal mitotic activity is identified.
+==See also==
+*[[Non-malignant skin disease]].
+==References==
+{{Reflist|2}}
 [[Category:Diagnosis]]
+[[Category:Non-malignant skin disease]]