Difference between revisions of "Hibernoma"
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'''Hibernoma''' is an uncommon tumour of brown fat. It is | {{ Infobox diagnosis | ||
| Name = {{PAGENAME}} | |||
| Image = Hibernoma1.jpg | |||
| Width = | |||
| Caption = Hibernoma. [[H&E stain]]. | |||
| Micro = large polygonal/oval cells with central & small nucleus; nucleoli typically prominent; cytoplasm multivacuolated, oval, eosinophilic, granular | |||
| Subtypes = | |||
| LMDDx = reaction to silicone implant | |||
| Stains = | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = lobulated lesion, light-brown, usually extremities | |||
| Grossing = | |||
| Site = [[soft tissue lesions|soft tissue]] - [[adipocytic lesions]] | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = young adults | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = uncommon | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = benign | |||
| Other = | |||
| ClinDDx = [[Lipoma]] | |||
}} | |||
'''Hibernoma''', also '''tumour of brown fat''',<ref>{{Cite journal | last1 = SHUTE | first1 = D. | title = Tumours of brown fat. | journal = Can Med Assoc J | volume = 71 | issue = 5 | pages = 484-5 | month = Nov | year = 1954 | doi = | PMID = 13209434 }}</ref> is an uncommon tumour of brown fat. It is grouped with the [[adipocytic tumours]]. | |||
==General== | ==General== | ||
Revision as of 13:45, 28 September 2013
| Hibernoma | |
|---|---|
| Diagnosis in short | |
 Hibernoma. H&E stain. | |
|
| |
| LM | large polygonal/oval cells with central & small nucleus; nucleoli typically prominent; cytoplasm multivacuolated, oval, eosinophilic, granular |
| LM DDx | reaction to silicone implant |
| Gross | lobulated lesion, light-brown, usually extremities |
| Site | soft tissue - adipocytic lesions |
|
| |
| Clinical history | young adults |
| Prevalence | uncommon |
| Prognosis | benign |
| Clin. DDx | Lipoma |
Hibernoma, also tumour of brown fat,[1] is an uncommon tumour of brown fat. It is grouped with the adipocytic tumours.
General
- Consists of brown fat (present in the infants to generate heat).[2]
- Benign.
- Usually asymptomatic.[3]
Epidemiology:
- Young adults.
Gross
- Well-circumscribed.
- Lobulated and light-brown on sectioning.
Microscopic
Features:[4]
- Large polygonal/oval cells:
- +/-Prominent blood vessels, central.[7]
DDx:
- Reaction to silicone implant.
Image
Hibernoma - high mag. (WC)
Hibernoma - intermed mag. (WC)
Hibernoma - low mag. (WC)
See also
References
- ↑ SHUTE, D. (Nov 1954). "Tumours of brown fat.". Can Med Assoc J 71 (5): 484-5. PMID 13209434.
- ↑ Humphrey, Peter A; Dehner, Louis P; Pfeifer, John D (2008). The Washington Manual of Surgical Pathology (1st ed.). Lippincott Williams & Wilkins. pp. 605. ISBN 978-0781765275.
- ↑ Ahmed SA, Schuller I (December 2008). "Pediatric hibernoma: a case review". J. Pediatr. Hematol. Oncol. 30 (12): 900–1. doi:10.1097/MPH.0b013e318184e6dd. PMID 19131775.
- ↑ Chen DY, Wang CM, Chan HL (March 1998). "Hibernoma. Case report and literature review". Dermatol Surg 24 (3): 393–5. PMID 9537018.
- ↑ http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675(06)70271-6
- ↑ http://surgpathcriteria.stanford.edu/softfat/hibernoma/
- ↑ URL: http://radiographics.rsna.org/content/24/5/1433.full. Accessed on: 11 February 2013.