Difference between revisions of "Osteoblastoma"
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Osteoblastoma_-_low_mag.jpg | |||
| Width = | |||
| Caption = Osteoblastoma. [[H&E stain]]. | |||
| Micro = anastomosing bony [[trabeculae]] with variable mineralization, osteoblast rimming, no nuclear atypia of osteocytes | |||
| Subtypes = | |||
| LMDDx = [[osteoid osteoma]], [[osteosarcoma]] | |||
| Stains = | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = | |||
| Bloodwork = | |||
| Rads = > 1.5 cm (smaller lesions [[osteoid osteoma]]) | |||
| Endoscopy = | |||
| Prognosis = | |||
| Other = | |||
| ClinDDx = [[osteosarcoma]] | |||
}} | |||
'''Osteoblastoma''' is benign primary [[bone tumour]]. | |||
==General== | |||
*Benign bone tumour. | |||
*Uncommon.<ref name=pmid23362588>{{Cite journal | last1 = Khan | first1 = IS. | last2 = Thakur | first2 = JD. | last3 = Chittiboina | first3 = P. | last4 = Nanda | first4 = A. | title = Large sacral osteoblastoma: a case report and review of multi-disciplinary management strategies. | journal = J La State Med Soc | volume = 164 | issue = 5 | pages = 251-5 | month = | year = | doi = | PMID = 23362588 }}</ref> | |||
==Gross== | |||
*Bone. | |||
**May be in the spine.<ref>{{Cite journal | last1 = Boriani | first1 = S. | last2 = Amendola | first2 = L. | last3 = Bandiera | first3 = S. | last4 = Simoes | first4 = CE. | last5 = Alberghini | first5 = M. | last6 = Di Fiore | first6 = M. | last7 = Gasbarrini | first7 = A. | title = Staging and treatment of osteoblastoma in the mobile spine: a review of 51 cases. | journal = Eur Spine J | volume = 21 | issue = 10 | pages = 2003-10 | month = Oct | year = 2012 | doi = 10.1007/s00586-012-2395-8 | PMID = 22695702 }}</ref> | |||
*'''Must''' be greater 1.5 cm by definition.<ref name=Ref_Sternberg4_286>{{Ref Sternberg4|286}}</ref> | |||
==Microscopic== | |||
Features:<ref name=Ref_Sternberg4_285>{{Ref Sternberg4|285}}</ref> | |||
*Anastomosing bony [[trabeculae]] with: | |||
**Osteoblasts rimming. | |||
***Cells line-up at edge of bone. | |||
Notes: | |||
*Histomorphologically near identical/indistinguishable from ''[[osteoid osteoma]]''.<ref name=Ref_Sternberg4_286>{{Ref Sternberg4|286}}</ref> | |||
===Images=== | |||
<gallery> | |||
Image:Osteoblastoma_-_high_mag.jpg | Osteoblastoma - high mag. (WC) | |||
Image:Osteoblastoma_-_low_mag.jpg | Osteoblastoma - low mag. (WC) | |||
</gallery> | |||
==Sign out== | |||
<pre> | |||
BONE, LEFT FEMUR, EXCISION: | |||
- OSTEOBLASTOMA. | |||
</pre> | |||
==See also== | |||
*[[Chondro-osseous tumours]]. | |||
*[[Bone]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Chondro-osseous tumours]] | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
Revision as of 21:23, 26 August 2013
| Osteoblastoma | |
|---|---|
| Diagnosis in short | |
 Osteoblastoma. H&E stain. | |
|
| |
| LM | anastomosing bony trabeculae with variable mineralization, osteoblast rimming, no nuclear atypia of osteocytes |
| LM DDx | osteoid osteoma, osteosarcoma |
| Radiology | > 1.5 cm (smaller lesions osteoid osteoma) |
| Clin. DDx | osteosarcoma |
Osteoblastoma is benign primary bone tumour.
General
- Benign bone tumour.
- Uncommon.[1]
Gross
Microscopic
Features:[4]
- Anastomosing bony trabeculae with:
- Osteoblasts rimming.
- Cells line-up at edge of bone.
- Osteoblasts rimming.
Notes:
- Histomorphologically near identical/indistinguishable from osteoid osteoma.[3]
Images
Osteoblastoma - high mag. (WC)
Osteoblastoma - low mag. (WC)
Sign out
BONE, LEFT FEMUR, EXCISION: - OSTEOBLASTOMA.
See also
References
- ↑ Khan, IS.; Thakur, JD.; Chittiboina, P.; Nanda, A.. "Large sacral osteoblastoma: a case report and review of multi-disciplinary management strategies.". J La State Med Soc 164 (5): 251-5. PMID 23362588.
- ↑ Boriani, S.; Amendola, L.; Bandiera, S.; Simoes, CE.; Alberghini, M.; Di Fiore, M.; Gasbarrini, A. (Oct 2012). "Staging and treatment of osteoblastoma in the mobile spine: a review of 51 cases.". Eur Spine J 21 (10): 2003-10. doi:10.1007/s00586-012-2395-8. PMID 22695702.
- ↑ 3.0 3.1 Mills, Stacey E; Carter, Darryl; Greenson, Joel K; Oberman, Harold A; Reuter, Victor E (2004). Sternberg's Diagnostic Surgical Pathology (4th ed.). Lippincott Williams & Wilkins. pp. 286. ISBN 978-0781740517.
- ↑ Mills, Stacey E; Carter, Darryl; Greenson, Joel K; Oberman, Harold A; Reuter, Victor E (2004). Sternberg's Diagnostic Surgical Pathology (4th ed.). Lippincott Williams & Wilkins. pp. 285. ISBN 978-0781740517.