Drug toxicity: Difference between revisions
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==Sodium polystyrene sulfonate== | ==Sodium polystyrene sulfonate== | ||
:[[AKA]] ''Kayexalate'' (trade name). | |||
===General=== | ===General=== | ||
*Used to treat hyperkalemia. | *Used to treat hyperkalemia. | ||
Revision as of 19:14, 19 August 2013
Drug toxicity, also drug reaction, in pathology is often a diagnosis of exclusion. Few drugs leave a distinctive histomorphologic pattern.
This article covers a few of the distinctive histomorphologic pattern and links to other articles that deal with specific organ systems.
Sodium polystyrene sulfonate
- AKA Kayexalate (trade name).
General
- Used to treat hyperkalemia.
Microscopic
Features:[1]
- Purple blobs on H&E stain - look somewhat like calcium phosphate.
- Can cause focal necrosis.
Image
-
Kayexalate crystals and adenocarcinoma. (WC)
See also
References
- ↑ Abraham SC, Bhagavan BS, Lee LA, Rashid A, Wu TT (May 2001). "Upper gastrointestinal tract injury in patients receiving kayexalate (sodium polystyrene sulfonate) in sorbitol: clinical, endoscopic, and histopathologic findings". Am. J. Surg. Pathol. 25 (5): 637-44. PMID 11342776. http://meta.wkhealth.com/pt/pt-core/template-journal/lwwgateway/media/landingpage.htm?issn=0147-5185&volume=25&issue=5&spage=637.