Difference between revisions of "Uterus"
Jump to navigation
Jump to search
(→Congenital absence: +uterine adenomyosis) |
|||
| Line 29: | Line 29: | ||
Treatment: | Treatment: | ||
*Uterine transplant - attempted.<ref>URL: [http://singularityhub.com/2011/06/18/in-a-medical-first-infertile-daughter-will-receive-uterus-from-mother-video/ http://singularityhub.com/2011/06/18/in-a-medical-first-infertile-daughter-will-receive-uterus-from-mother-video/]. Accessed on: 17 June 2011.</ref> | *Uterine transplant - attempted.<ref>URL: [http://singularityhub.com/2011/06/18/in-a-medical-first-infertile-daughter-will-receive-uterus-from-mother-video/ http://singularityhub.com/2011/06/18/in-a-medical-first-infertile-daughter-will-receive-uterus-from-mother-video/]. Accessed on: 17 June 2011.</ref> | ||
==Uterine adenomyosis== | |||
===General=== | |||
*Common - may be a cause of bleeding.<ref>{{Cite journal | last1 = Reinhold | first1 = C. | last2 = Tafazoli | first2 = F. | last3 = Mehio | first3 = A. | last4 = Wang | first4 = L. | last5 = Atri | first5 = M. | last6 = Siegelman | first6 = ES. | last7 = Rohoman | first7 = L. | title = Uterine adenomyosis: endovaginal US and MR imaging features with histopathologic correlation. | journal = Radiographics | volume = 19 Spec No | issue = | pages = S147-60 | month = Oct | year = 1999 | doi = | PMID = 10517451 | URL = http://radiographics.rsna.org/content/19/suppl_1/S147.full }}</ref> | |||
*Associated with [[endometriosis]]. (???) | |||
===Microscopic=== | |||
Features: | |||
*Endometrial glands within uterine muscle - '''key feature'''. | |||
**Endometrial glands: | |||
***Circular. | |||
***Simple epithelial or pseudostratified epithelium +/- mitoses. | |||
**+/-Surrounded by endometrial stroma. | |||
***Densely packed spindle cells without [[nuclear atypia]]. | |||
**Blood: | |||
***Within glands. | |||
***Hemosiderin-laden macrophages. | |||
Note: | |||
*Can be thought of as [[endometriosis]] of the myometrium. | |||
DDx: | |||
*[[Endometrioid endometrial carcinoma]]. | |||
==See also== | ==See also== | ||
Revision as of 14:17, 17 December 2011
The uterus is essential for survival of the species. It is commonly afflicted with tumours.
Endometrium and its pathology is dealt with in the endometrium, endometrial hyperplasia and endometrial carcinoma articles.
Other tumours are dealt with in uterine tumours.
Operations
- Subtotal hysterectomy.
- Total hysterectomy.
Notes:
- There are almost no quality of life differences between total & subtotal hysterectomy.[1]
Tumours of the corpus
Main article: Uterine tumours
The most common is leiomyoma (uterine fibroids).
Endometrium
Main article: Endometrium
Dealt with in endometrium, endometrial hyperplasia and endometrial carcinoma articles.
Congenital absence
- Often in association with vaginal absence; ergo congenital absence of the uterus and vagina (CAUV).
Features:[2]
- Subdivided - as etiologies differ.
- Thought to have a genetic component - autosomal dominant with variable penetration.
Treatment:
- Uterine transplant - attempted.[3]
Uterine adenomyosis
General
- Common - may be a cause of bleeding.[4]
- Associated with endometriosis. (???)
Microscopic
Features:
- Endometrial glands within uterine muscle - key feature.
- Endometrial glands:
- Circular.
- Simple epithelial or pseudostratified epithelium +/- mitoses.
- +/-Surrounded by endometrial stroma.
- Densely packed spindle cells without nuclear atypia.
- Blood:
- Within glands.
- Hemosiderin-laden macrophages.
- Endometrial glands:
Note:
- Can be thought of as endometriosis of the myometrium.
DDx:
See also
References
- ↑ Thakar, R.; Ayers, S.; Clarkson, P.; Stanton, S.; Manyonda, I. (Oct 2002). "Outcomes after total versus subtotal abdominal hysterectomy.". N Engl J Med 347 (17): 1318-25. doi:10.1056/NEJMoa013336. PMID 12397189.
- ↑ 2.0 2.1 URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1832178/.
- ↑ URL: http://singularityhub.com/2011/06/18/in-a-medical-first-infertile-daughter-will-receive-uterus-from-mother-video/. Accessed on: 17 June 2011.
- ↑ Reinhold, C.; Tafazoli, F.; Mehio, A.; Wang, L.; Atri, M.; Siegelman, ES.; Rohoman, L. (Oct 1999). "Uterine adenomyosis: endovaginal US and MR imaging features with histopathologic correlation.". Radiographics 19 Spec No: S147-60. PMID 10517451.