Difference between revisions of "Cervical polyps"
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(+other types of polyps) |
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*Cause bleeding - due to trauma (???). | *Cause bleeding - due to trauma (???). | ||
=== | ===Microscopic=== | ||
Features: | |||
*May have mixed epithelium, i.e. squamous and endocervical type (with eosinophilic mucin). | *May have mixed epithelium, i.e. squamous and endocervical type (with eosinophilic mucin). | ||
**Endocervical epithelium should have nuclei like that in the colon, i.e. small, round & basal. | **Endocervical epithelium should have nuclei like that in the colon, i.e. small, round & basal. | ||
| Line 16: | Line 17: | ||
*No mitoses. | *No mitoses. | ||
*No nuclear atypia. | *No nuclear atypia. | ||
*No stromal proliferation. | |||
Notes: | Notes: | ||
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Ref.:<ref>[http://pathologyoutlines.com/cervix.html#endocervpolyp http://pathologyoutlines.com/cervix.html#endocervpolyp]</ref> | Ref.:<ref>[http://pathologyoutlines.com/cervix.html#endocervpolyp http://pathologyoutlines.com/cervix.html#endocervpolyp]</ref> | ||
==Fibroepithelial stromal polyp== | |||
===General=== | |||
*Usually easy to recognize.<ref name=pmid10680891/> | |||
===Microscopic=== | |||
Features:<ref name=pmid10680891/> | |||
*Bland nuclei. | |||
*Hypocellular. | |||
==Pseudosarcomatous fibroepithelial stromal polyp== | |||
===General=== | |||
*Uncommon. | |||
*Wide age range. | |||
*May be misdiagnosed as a sarcoma and overtreated.<ref name=pmid10680891>{{Cite journal | last1 = Nucci | first1 = MR. | last2 = Young | first2 = RH. | last3 = Fletcher | first3 = CD. | title = Cellular pseudosarcomatous fibroepithelial stromal polyps of the lower female genital tract: an underrecognized lesion often misdiagnosed as sarcoma. | journal = Am J Surg Pathol | volume = 24 | issue = 2 | pages = 231-40 | month = Feb | year = 2000 | doi = | PMID = 10680891 }}</ref> | |||
*Similar lesions in [[vagina]] and [[vulva]]. | |||
===Microscopic=== | |||
Features:<ref name=pmid10680891/> | |||
*Hypercellularity. | |||
*Marked nuclear pleomorphism (common). | |||
*+/-High mitotic rate ( > 10 mitoses / 10 [[HPF]]). | |||
*+/-Atypical mitoses. | |||
*No identifiable margin between lesion and normal - important feature. | |||
*Scattered multinucleated stromal cells - usu. close to epithelium. | |||
===IHC=== | |||
*Desmin +ve (common). | |||
*SMA usu. -ve. | |||
==See also== | ==See also== | ||
*[[Endometrial polyp]]. | *[[Endometrial polyp]]. | ||
Revision as of 15:48, 8 August 2011
Cervical polyps are common entities that can be bothersome and are thus removed.
Endocervical polyps
Clinical
- Usually 30-50 years old.
- Cause bleeding - due to trauma (???).
Microscopic
Features:
- May have mixed epithelium, i.e. squamous and endocervical type (with eosinophilic mucin).
- Endocervical epithelium should have nuclei like that in the colon, i.e. small, round & basal.
- Polypoid shape.
- +/-Inflammation.
- +/-Squamous metaplasia.
Negatives:
- No mitoses.
- No nuclear atypia.
- No stromal proliferation.
Notes:
- No histologic features separate cervical polyps from benign endocervical mucosa; ergo, they are often signed-out as "... consistent with cervical polyp."
Ref.:[1]
Fibroepithelial stromal polyp
General
- Usually easy to recognize.[2]
Microscopic
Features:[2]
- Bland nuclei.
- Hypocellular.
Pseudosarcomatous fibroepithelial stromal polyp
General
- Uncommon.
- Wide age range.
- May be misdiagnosed as a sarcoma and overtreated.[2]
- Similar lesions in vagina and vulva.
Microscopic
Features:[2]
- Hypercellularity.
- Marked nuclear pleomorphism (common).
- +/-High mitotic rate ( > 10 mitoses / 10 HPF).
- +/-Atypical mitoses.
- No identifiable margin between lesion and normal - important feature.
- Scattered multinucleated stromal cells - usu. close to epithelium.
IHC
- Desmin +ve (common).
- SMA usu. -ve.
See also
References
- ↑ http://pathologyoutlines.com/cervix.html#endocervpolyp
- ↑ 2.0 2.1 2.2 2.3 Nucci, MR.; Young, RH.; Fletcher, CD. (Feb 2000). "Cellular pseudosarcomatous fibroepithelial stromal polyps of the lower female genital tract: an underrecognized lesion often misdiagnosed as sarcoma.". Am J Surg Pathol 24 (2): 231-40. PMID 10680891.