Difference between revisions of "Sarcina"

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Image: Gastritis with Sarcina - a1 - very high mag.jpg | Sarcina - very high mag.
Image: Gastritis with Sarcina - a1 - very high mag.jpg | Sarcina - very high mag.
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====Case 2====
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Image: Sarcina - urine -- intermed mag.jpg | Sarcina - urine cytology - intermed. mag.
Image: Sarcina - urine -- high mag.jpg | Sarcina - urine cytology - high mag.
Image: Sarcina - urine - alt -- high mag.jpg | Sarcina - urine cytology - high mag.
Image: Sarcina - urine -- very high mag.jpg | Sarcina - urine cytology - very high mag.
Image: Sarcina - urine -- extremely high mag.jpg | Sarcina - urine cytology - extremely high mag.
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*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193598/figure/F2/ Sarcina (nih.gov)].
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193598/figure/F2/ Sarcina (nih.gov)].

Latest revision as of 23:36, 3 November 2024

Micrograph showing Sarcina. H&E stain. (WC/Librepath)

Sarcina organisms are occasionally seen in the gastrointestinal tract. They are reported in urine.[1]

General

  • Probably a commensal organism.[2]
  • Gram positive coccus.[1]
  • Uncommonly seen.
  • Associated with gastroparesis,[2] as may be seen in diabetes mellitus.

Described complications:[2]

  • Gastric perforation.
  • Emphysematous gastritis.

Notes:

  • Sarcina ventriculi = Gram-positive organism.[2]

Gross

Features:

  • Erythema.
  • +/-Gastric ulcer.
  • +/-Retained food.

Microscopic

Features:[3]

  • Small essentially spherical micro-organisms.
    • Each micro-organism 1.8-3 micrometres - purple on H&E stain.
    • Arranged in clusters of 4, 8 or more - classically in a tetrad - key feature.

DDx:

  • Micrococcus - form larger clusters.[3]

Images

Case 1

  • Sarcina - low mag.

  • Sarcina - intermed. mag.

  • Sarcina - intermed. mag.

  • Sarcina - high mag.

  • Sarcina - high mag.

  • Sarcina - very high mag.

  • Sarcina - very high mag.

Case 2

  • Sarcina - urine cytology - intermed. mag.

  • Sarcina - urine cytology - high mag.

  • Sarcina - urine cytology - high mag.

  • Sarcina - urine cytology - very high mag.

  • Sarcina - urine cytology - extremely high mag.

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Urine cytology

Abundant micro-organisms compatible with Sarcina, see comment.
Acute inflammation.
NEGATIVE for High-Grade Urothelial Carcinoma.

Comment:
The micro-organisms are arranged in distinctive tetrads, as is typical for Sarcina.
This is an uncommon finding.[1] Treatment should be considered within the clinical context.

1. Bommannan K, Gaspar BL, Sachdeva MUS. BMJ Case Rep. 2016 Oct 13;2016:bcr2016216991. doi:10.1136/bcr-2016-216991
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073697/pdf/bcr-2016-216991.pdf

See also

References

  1. ↑ 1.0 1.1 Bommannan K, Gaspar BL, Sachdeva MU (October 2016). "Pathogenic Sarcina in urine". BMJ Case Rep 2016. doi:10.1136/bcr-2016-216991. PMC 5073697. PMID 27737866. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073697/.
  2. ↑ 2.0 2.1 2.2 2.3 2.4 Ratuapli, SK.; Lam-Himlin, DM.; Heigh, RI. (2013). "Sarcina ventriculi of the stomach: a case report.". World J Gastroenterol 19 (14): 2282-5. doi:10.3748/wjg.v19.i14.2282. PMID 23599657.
  3. ↑ 3.0 3.1 Lam-Himlin, D.; Tsiatis, AC.; Montgomery, E.; Pai, RK.; Brown, JA.; Razavi, M.; Lamps, L.; Eshleman, JR. et al. (Nov 2011). "Sarcina organisms in the gastrointestinal tract: a clinicopathologic and molecular study.". Am J Surg Pathol 35 (11): 1700-5. doi:10.1097/PAS.0b013e31822911e6. PMID 21997690.
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