Difference between revisions of "PEComa"
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*Central oval (or round) nucleus. | *Central oval (or round) nucleus. | ||
**Indistinct/small nucleolus. | **Indistinct/small nucleolus. | ||
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*[[Clear cell sarcoma]]. | |||
Images: | Images: | ||
Revision as of 17:14, 29 April 2011
PEComa is a family of tumours derived from perivascular epithelioid cells (PECs).
General
- Associated with abnormalities in TSC1 and TSC2 - the genes involved in tuberous sclerosis.[1]
The PEComa family
- Angiomyolipoma.
- Lymphangioleiomyomatosis.
- Clear-cell myomelanocytic tumour of ligamentum teres/falciform ligament.
- Abdominopelvic sarcoma of perivascular epitheloid cells.
- Clear-cell sugar tumour (CCST).
- Primary extrapulmonary sugar tumour.
Microscopic
Features:[1]
- Epithelioid morphology.
- Clear or granular cytoplasm.
- Central oval (or round) nucleus.
- Indistinct/small nucleolus.
DDx:
Images:
IHC
See also
References
- ↑ 1.0 1.1 1.2 1.3 Martignoni G, Pea M, Reghellin D, Zamboni G, Bonetti F (February 2008). "PEComas: the past, the present and the future". Virchows Arch. 452 (2): 119–32. doi:10.1007/s00428-007-0509-1. PMC 2234444. PMID 18080139. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234444/.