Difference between revisions of "Eosinophilic granulomatosis with polyangiitis"
Jump to navigation
Jump to search
(+infobox) |
m (fix typo) |
||
| Line 7: | Line 7: | ||
| Micro = small vessel [[vasculitis]] with abundant eosinophils and [[granuloma]]s | | Micro = small vessel [[vasculitis]] with abundant eosinophils and [[granuloma]]s | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = | | LMDDx = eosinophilic vasculitis associated with a [[connective tissue disease]] | ||
| Stains = | | Stains = | ||
| IHC = | | IHC = | ||
Revision as of 21:19, 28 November 2016
| Eosinophilic granulomatosis with polyangiitis | |
|---|---|
| Diagnosis in short | |
 Eosinophilic granulomatosis with polyangiitis. H&E stain. | |
|
| |
| LM | small vessel vasculitis with abundant eosinophils and granulomas |
| LM DDx | eosinophilic vasculitis associated with a connective tissue disease |
| Site | blood vessels |
|
| |
| Associated Dx | asthma |
| Signs | fever |
| Prevalence | rare |
Eosinophilic granulomatosis with polyangiitis, previously known as Churg-Strauss syndrome,[1] is a type of vasculitis.
General
Defining features - memory device GAFE:
- Granulomata.
- Asthma.
- Fever.
- Eosinophilia.
Notes:
- Similar to Granulomatosis with polyangiitis (Wegener's granulomatosis) - classically c-ANCA +ve, and microscopic polyangiitis.[2]
Microscopic
Features:
- Small vessel vasculitis.
- Abundant eosinophils.
- Granulomas.
DDx:
- Eosinophilic vasculitis associated with a connective tissue disease.[3]
Images
CSS - high mag. (WC)
CSS - very high mag. (WC)
See also
References
- ↑ Stone, JR.; Bruneval, P.; Angelini, A.; Bartoloni, G.; Basso, C.; Batoroeva, L.; Buja, LM.; Butany, J. et al. "Consensus statement on surgical pathology of the aorta from the Society for Cardiovascular Pathology and the Association for European Cardiovascular Pathology: I. Inflammatory diseases.". Cardiovasc Pathol 24 (5): 267-78. doi:10.1016/j.carpath.2015.05.001. PMID 26051917.
- ↑ URL: http://emedicine.medscape.com/article/334024-overview. Accessed on: 22 January 2011.
- ↑ Chen, KR.; Su, WP.; Pittelkow, MR.; Conn, DL.; George, T.; Leiferman, KM. (Aug 1996). "Eosinophilic vasculitis in connective tissue disease.". J Am Acad Dermatol 35 (2 Pt 1): 173-82. PMID 8708015.