Difference between revisions of "Pulmonary neuroendocrine cell hyperplasia"
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==Microscopic== | ==Microscopic== | ||
Features: | Features: | ||
* | *Proliferation of neuroendocrine cells - confined by the basement membrane of the bronchus.<ref name=pmid20729444>{{Cite journal | last1 = Koo | first1 = CW. | last2 = Baliff | first2 = JP. | last3 = Torigian | first3 = DA. | last4 = Litzky | first4 = LA. | last5 = Gefter | first5 = WB. | last6 = Akers | first6 = SR. | title = Spectrum of pulmonary neuroendocrine cell proliferation: diffuse idiopathic pulmonary neuroendocrine cell hyperplasia, tumorlet, and carcinoids. | journal = AJR Am J Roentgenol | volume = 195 | issue = 3 | pages = 661-8 | month = Sep | year = 2010 | doi = 10.2214/AJR.09.3811 | PMID = 20729444 }}</ref> | ||
**Salt and pepper chromatin. | **Salt and pepper chromatin. | ||
Revision as of 19:17, 25 September 2015
Pulmonary neuroendocrine cell hyperplasia is a proliferation of neuroendocrine cells confined by the bronchial basement membrane.
General
- Common.
- May be seen in the context of diffuse idiopathic pulmonary neuroendocrine cell hyperplasia.
Microscopic
Features:
- Proliferation of neuroendocrine cells - confined by the basement membrane of the bronchus.[1]
- Salt and pepper chromatin.
Note:
- They often project into the airway.
DDx:
- Carcinoid tumourlet - extends beyond the basement membrane and less than 5 mm in maximal dimension.
See also
References
- ↑ Koo, CW.; Baliff, JP.; Torigian, DA.; Litzky, LA.; Gefter, WB.; Akers, SR. (Sep 2010). "Spectrum of pulmonary neuroendocrine cell proliferation: diffuse idiopathic pulmonary neuroendocrine cell hyperplasia, tumorlet, and carcinoids.". AJR Am J Roentgenol 195 (3): 661-8. doi:10.2214/AJR.09.3811. PMID 20729444.