Difference between revisions of "Fuchs dystrophy"

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**Collagenous material from the basement membrane.
**Collagenous material from the basement membrane.
*Decreased endothelial density.<ref name=pmid19236704>{{Cite journal  | last1 = Klintworth | first1 = GK. | title = Corneal dystrophies. | journal = Orphanet J Rare Dis | volume = 4 | issue =  | pages = 7 | month =  | year = 2009 | doi = 10.1186/1750-1172-4-7 | PMID = 19236704 }}</ref>
*Decreased endothelial density.<ref name=pmid19236704>{{Cite journal  | last1 = Klintworth | first1 = GK. | title = Corneal dystrophies. | journal = Orphanet J Rare Dis | volume = 4 | issue =  | pages = 7 | month =  | year = 2009 | doi = 10.1186/1750-1172-4-7 | PMID = 19236704 }}</ref>
*Thickening of ''Descemet's membrane''.<ref>URL: [http://www.mrcophth.com/pathology/fuchendothelialdystrophy.html http://www.mrcophth.com/pathology/fuchendothelialdystrophy.html]. Accessed on: 27 August 2015.</ref>


===Images===
===Images===

Revision as of 16:06, 27 August 2015

Fuchs dystrophy, also Fuchs endothelial dystrophy, is a rare pathology of the eye that may be seen in Descemet's membrane specimens.

General

  • Uncommon.

Microscopic

Features:[1]

  • Guttae accumulations.
    • Collagenous material from the basement membrane.
  • Decreased endothelial density.[2]
  • Thickening of Descemet's membrane.[3]

Images

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Decemet's Membrane, Right Eye, Excision:
- Loss of endothelial cells and guttata formation compatible with Fuch's dystrophy.

See also

References

  1. McLaren, JW.; Bachman, LA.; Kane, KM.; Patel, SV. (Feb 2014). "Objective assessment of the corneal endothelium in Fuchs' endothelial dystrophy.". Invest Ophthalmol Vis Sci 55 (2): 1184-90. doi:10.1167/iovs.13-13041. PMID 24508788.
  2. 2.0 2.1 Klintworth, GK. (2009). "Corneal dystrophies.". Orphanet J Rare Dis 4: 7. doi:10.1186/1750-1172-4-7. PMID 19236704.
  3. URL: http://www.mrcophth.com/pathology/fuchendothelialdystrophy.html. Accessed on: 27 August 2015.