Difference between revisions of "Urinary bladder xanthoma"
Jump to navigation
Jump to search
(create) |
(+SO) |
||
| Line 1: | Line 1: | ||
'''Urinary bladder xanthoma''', also '''[[xanthoma]] of the [[urinary bladder]]''', is a rare benign lesion of the bladder that occasionally may be clinically suspicious for malignancy.<ref name=pmid24810457>{{Cite journal | last1 = Hassouna | first1 = H. | last2 = Broome | first2 = JD. | last3 = Swalem | first3 = K. | last4 = Manikandan | first4 = R. | title = Xanthoma of the urinary bladder: a rare benign condition which may be mistaken for malignancy. | journal = BMJ Case Rep | volume = 2014 | issue = | pages = | month = | year = 2014 | doi = 10.1136/bcr-2014-203836 | PMID = 24810457 }}</ref> | '''Urinary bladder xanthoma''', also '''[[xanthoma]] of the [[urinary bladder]]''' and '''bladder xanthoma''', is a rare benign lesion of the bladder that occasionally may be clinically suspicious for [[malignancy]].<ref name=pmid24810457>{{Cite journal | last1 = Hassouna | first1 = H. | last2 = Broome | first2 = JD. | last3 = Swalem | first3 = K. | last4 = Manikandan | first4 = R. | title = Xanthoma of the urinary bladder: a rare benign condition which may be mistaken for malignancy. | journal = BMJ Case Rep | volume = 2014 | issue = | pages = | month = | year = 2014 | doi = 10.1136/bcr-2014-203836 | PMID = 24810457 }}</ref> | ||
==General== | ==General== | ||
| Line 29: | Line 29: | ||
*S-100 -ve | *S-100 -ve | ||
**Positive in granular cell tumour. | **Positive in granular cell tumour. | ||
==Sign out== | |||
<pre> | |||
Urinary Bladder Lesion, Transurethral Excision: | |||
- Xanthoma, see comment. | |||
COMMENT: | |||
These lesions may be associated metabolic abnormalities. A lipid profile | |||
should be considered. | |||
</pre> | |||
==See also== | ==See also== | ||
Revision as of 16:29, 22 July 2015
Urinary bladder xanthoma, also xanthoma of the urinary bladder and bladder xanthoma, is a rare benign lesion of the bladder that occasionally may be clinically suspicious for malignancy.[1]
General
- Rare.
- Like other xanthomas may be associated with abnormal lipid profile.
Presentation:[2]
- Hematuria.
- Irritation.
Gross
Features:[2]
Microscopic
Features:
- Aggregate of foamy histiocytes in the lamina propria.[2]
- No significant nuclear atypia.
DDx:[2]
- Signet ring cell carcinoma.
- Granular cell tumour.
- Malakoplakia.
- Xanthogranulomatous cystitis.
- Mild urothelial atypia (esp. large umbrella cells) in normal urothelium.
IHC
- CD68 +ve.
- S-100 -ve
- Positive in granular cell tumour.
Sign out
Urinary Bladder Lesion, Transurethral Excision: - Xanthoma, see comment. COMMENT: These lesions may be associated metabolic abnormalities. A lipid profile should be considered.
See also
References
- ↑ Hassouna, H.; Broome, JD.; Swalem, K.; Manikandan, R. (2014). "Xanthoma of the urinary bladder: a rare benign condition which may be mistaken for malignancy.". BMJ Case Rep 2014. doi:10.1136/bcr-2014-203836. PMID 24810457.
- ↑ 2.0 2.1 2.2 2.3 Yu, DC.; Patel, P.; Bonert, M.; Carlson, K.; Yilmaz, A.; Paner, G.; Magi-Galluzzi, C.; Lopez-Beltran, A. et al. (Aug 2015). "Urinary bladder xanthoma: a multi-institutional series of 17 cases.". Histopathology 67 (2): 255-61. doi:10.1111/his.12647. PMID 25580863.