Difference between revisions of "Glycogenic acanthosis of the esophagus"

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*Uncommon - seen 3.5% of consecutive 2328 upper endoscopies.<ref name=pmid8409304>{{Cite journal  | last1 = Vadva | first1 = MD. | last2 = Triadafilopoulos | first2 = G. | title = Glycogenic acanthosis of the esophagus and gastroesophageal reflux. | journal = J Clin Gastroenterol | volume = 17 | issue = 1 | pages = 79-83 | month = Jul | year = 1993 | doi =  | PMID = 8409304 }}</ref>
*Uncommon - seen 3.5% of consecutive 2328 upper endoscopies.<ref name=pmid8409304>{{Cite journal  | last1 = Vadva | first1 = MD. | last2 = Triadafilopoulos | first2 = G. | title = Glycogenic acanthosis of the esophagus and gastroesophageal reflux. | journal = J Clin Gastroenterol | volume = 17 | issue = 1 | pages = 79-83 | month = Jul | year = 1993 | doi =  | PMID = 8409304 }}</ref>
*Benign.<ref name=pmid25632181>{{Cite journal  | last1 = Tsai | first1 = SJ. | last2 = Lin | first2 = CC. | last3 = Chang | first3 = CW. | last4 = Hung | first4 = CY. | last5 = Shieh | first5 = TY. | last6 = Wang | first6 = HY. | last7 = Shih | first7 = SC. | last8 = Chen | first8 = MJ. | title = Benign esophageal lesions: endoscopic and pathologic features. | journal = World J Gastroenterol | volume = 21 | issue = 4 | pages = 1091-8 | month = Jan | year = 2015 | doi = 10.3748/wjg.v21.i4.1091 | PMID = 25632181 }}</ref>
*Benign.<ref name=pmid25632181>{{Cite journal  | last1 = Tsai | first1 = SJ. | last2 = Lin | first2 = CC. | last3 = Chang | first3 = CW. | last4 = Hung | first4 = CY. | last5 = Shieh | first5 = TY. | last6 = Wang | first6 = HY. | last7 = Shih | first7 = SC. | last8 = Chen | first8 = MJ. | title = Benign esophageal lesions: endoscopic and pathologic features. | journal = World J Gastroenterol | volume = 21 | issue = 4 | pages = 1091-8 | month = Jan | year = 2015 | doi = 10.3748/wjg.v21.i4.1091 | PMID = 25632181 }}</ref>
*May be associated with [[GERD]];<ref name=pmid8409304/> however, lesions do not resolve with [[Proton pump inhibitor|PPI]] treatment.<ref name=pmid25632181/>
*May be associated with [[GERD]];<ref name=pmid8409304/><ref name=pmid22798107>{{Cite journal  | last1 = Nazligül | first1 = Y. | last2 = Aslan | first2 = M. | last3 = Esen | first3 = R. | last4 = Yeniova | first4 = AÖ. | last5 = Kefeli | first5 = A. | last6 = Küçükazman | first6 = M. | last7 = Dülger | first7 = AC. | last8 = Celik | first8 = Y. | title = Benign glycogenic acanthosis lesions of the esophagus. | journal = Turk J Gastroenterol | volume = 23 | issue = 3 | pages = 199-202 | month = Jun | year = 2012 | doi =  | PMID = 22798107 }}</ref> however, lesions do not resolve with [[Proton pump inhibitor|PPI]] treatment.<ref name=pmid25632181/>
*Possible association with ingestion of hot liquids.<ref name=pmid20524767/>
*Possible association with ingestion of hot liquids.<ref name=pmid20524767/>


Revision as of 10:24, 16 May 2015

Glycogenic acanthosis of the esophagus
Diagnosis in short
LM squamous epithelium with (1) superficial clearing of the cytoplasm, and (2) thickening
Site esophagus
Associated Dx gastroesophageal reflux disease (???)
Clinical history ingestion of hot liquids (???)
Prevalence uncommon
Endoscopy raised grey/white lesions
Prognosis benign

Glycogenic acanthosis of the esophagus is an uncommon benign change of the esophagus with a distinctive endoscopic appearance.

General

  • Uncommon - seen 3.5% of consecutive 2328 upper endoscopies.[1]
  • Benign.[2]
  • May be associated with GERD;[1][3] however, lesions do not resolve with PPI treatment.[2]
  • Possible association with ingestion of hot liquids.[4]

Gross/endoscopic

  • Distinctive endoscopic appearance - grey/white raised lesion.[4]

Image

Microscopic

Features:[4]

  • Squamous epithelium with:
    • Superficial clearing of the cytoplasm.
    • Thickening.

Images

  • GAE - low mag.

  • GAE - intermed. mag.

  • GAE - intermed. mag.

  • GAE - high mag.

  • GAE - intermed. mag.

  • GAE - high mag.

www

See also

References

  1. ↑ 1.0 1.1 Vadva, MD.; Triadafilopoulos, G. (Jul 1993). "Glycogenic acanthosis of the esophagus and gastroesophageal reflux.". J Clin Gastroenterol 17 (1): 79-83. PMID 8409304.
  2. ↑ 2.0 2.1 2.2 Tsai, SJ.; Lin, CC.; Chang, CW.; Hung, CY.; Shieh, TY.; Wang, HY.; Shih, SC.; Chen, MJ. (Jan 2015). "Benign esophageal lesions: endoscopic and pathologic features.". World J Gastroenterol 21 (4): 1091-8. doi:10.3748/wjg.v21.i4.1091. PMID 25632181.
  3. ↑ Nazligül, Y.; Aslan, M.; Esen, R.; Yeniova, AÖ.; Kefeli, A.; Küçükazman, M.; Dülger, AC.; Celik, Y. (Jun 2012). "Benign glycogenic acanthosis lesions of the esophagus.". Turk J Gastroenterol 23 (3): 199-202. PMID 22798107.
  4. ↑ 4.0 4.1 4.2 Lopes, S.; Figueiredo, P.; Amaro, P.; Freire, P.; Alves, S.; Cipriano, MA.; Gouveia, H.; Sofia, C. et al. (May 2010). "Glycogenic acanthosis of the esophagus: an unusually endoscopic appearance.". Rev Esp Enferm Dig 102 (5): 341-2. PMID 20524767.
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