Difference between revisions of "Thecoma"
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'''Thecoma''' is an [[ovarian tumour]] | '''Thecoma''' is an [[ovarian tumour|ovarian]] [[Sex cord-stromal tumours|sex-cord stromal tumour]]. | ||
==General== | ==General== | ||
| Line 8: | Line 8: | ||
==Gross== | ==Gross== | ||
Features: | Features: | ||
*Solid yellow mass, | *Solid yellow mass, usually well-circumscribed.<ref name=Ref_AoGP398>{{Ref AoGP|398}}</ref> | ||
DDx: | DDx: | ||
| Line 27: | Line 27: | ||
==IHC== | ==IHC== | ||
*Alpha-inhibin +ve (90%+).<ref name=pmid16810055/> | *Alpha-inhibin +ve (90%+).<ref name=pmid16810055/> | ||
==See also== | |||
*[[Ovarian tumours]]. | |||
*[[Ovarian fibroma]]. | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Ovarian tumours]] | [[Category:Ovarian tumours]] | ||
Revision as of 05:38, 2 May 2015
Thecoma is an ovarian sex-cord stromal tumour.
General
- Associated with compression & atrophy of ovarian cortex, thought to arise from medulla.[1]
- Approximately 50% have symptoms related to estrogen secretion.[2]
- May also be viralizing.
Gross
Features:
- Solid yellow mass, usually well-circumscribed.[3]
DDx:
- Ovarian fibroma - white solid mass.[3]
- Fibroma-thecoma (fibrothecoma).
Microscopic
Features:[2]
- Nuclei with oval to spindle morphology.
- Abundant cytoplasm that is pale, vaculolated -- key feature.
Images
Thecoma - low mag. (WC)
Thecoma - high mag. (WC)
IHC
- Alpha-inhibin +ve (90%+).[2]
See also
References
- ↑ Nocito, AL.; Sarancone, S.; Bacchi, C.; Tellez, T. (Feb 2008). "Ovarian thecoma: clinicopathological analysis of 50 cases.". Ann Diagn Pathol 12 (1): 12-6. doi:10.1016/j.anndiagpath.2007.01.011. PMID 18164409.
- ↑ 2.0 2.1 2.2 Roth, LM. (Jul 2006). "Recent advances in the pathology and classification of ovarian sex cord-stromal tumors.". Int J Gynecol Pathol 25 (3): 199-215. doi:10.1097/01.pgp.0000192271.22289.e6. PMID 16810055.
- ↑ 3.0 3.1 Rose, Alan G. (2008). Atlas of Gross Pathology with Histologic Correlation (1st ed.). Cambridge University Press. pp. 398. ISBN 978-0521868792.