Difference between revisions of "Post-infectious glomerulonephritis"
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Revision as of 06:10, 11 April 2015
Post-infectious glomerulonephritis, abbreviated PIGN, is a rarely biopsied glomerulonephritis classically associated with a streptococcal infection.
General
- Classically post-streptococcal infection.
- Lab test: Antistreptolysin O titer (ASOT) +ve.
Microscopic
Features:
- +/-Neutrophils - in glomerulus.
- Glomerular crescents.
Images
Post-infectious GN - high mag. (WC/Nephron)
Post-infectious GN - very high mag. (WC/Nephron)
Post-infectious GN - schematic (WC/Nephron)
www:
IF
- Granular immune deposits.
EM
- Subepithelial deposits - hump-like.
- Larger when measured perpendicular to the basement membrane, if compared to membranous nephropathy.
- Typically focal.