Difference between revisions of "Testicular adrenal rest tumour"
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===Images=== | ===Images=== | ||
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037253/figure/f4-jrcr-8-2-46/ TART (nih.gov)]. | *[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037253/figure/f4-jrcr-8-2-46/ TART (nih.gov)]. | ||
==IHC== | |||
*Melan A +ve.<ref name=pmid20951518>{{Cite journal | last1 = Mizukami | first1 = H. | last2 = Hamamatsu | first2 = A. | last3 = Mori | first3 = S. | last4 = Hara | first4 = S. | last5 = Kuroda | first5 = M. | last6 = Nagai | first6 = T. | last7 = Fukunaga | first7 = T. | title = Autopsy and genetic diagnosis of 21-hydroxylase deficiency with bilateral testicular tumors in a case under no medication for over one year. | journal = Forensic Sci Int | volume = 206 | issue = 1-3 | pages = e71-5 | month = Mar | year = 2011 | doi = 10.1016/j.forsciint.2010.09.017 | PMID = 20951518 }}</ref> | |||
==See also== | ==See also== | ||
Revision as of 20:56, 11 December 2014
Testicular adrenal rest tumour, abbreviated TART, is a rare tumour associated with increased ACTH, typically seen in the context of congenital adrenal hyperplasia.[1]
General
- Very rare.
Clinical:
- Serum ACTH elevated.
Microscopic
Features:
- Nests of eosinophilic cells interspersed with thin bands of fibrous tissue.
- Mild (endocrine) nuclear atypia.
DDx:
- Leydig cell tumour - history different.
Images
IHC
- Melan A +ve.[2]
See also
References
- ↑ Olpin, JD.; Witt, B. (Feb 2014). "Testicular adrenal rest tumors in a patient with congenital adrenal hyperplasia.". J Radiol Case Rep 8 (2): 46-53. doi:10.3941/jrcr.v8i2.1489. PMID 24967019.
- ↑ Mizukami, H.; Hamamatsu, A.; Mori, S.; Hara, S.; Kuroda, M.; Nagai, T.; Fukunaga, T. (Mar 2011). "Autopsy and genetic diagnosis of 21-hydroxylase deficiency with bilateral testicular tumors in a case under no medication for over one year.". Forensic Sci Int 206 (1-3): e71-5. doi:10.1016/j.forsciint.2010.09.017. PMID 20951518.