Difference between revisions of "Negative prostatectomy"
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#*Is it plausible? | #*Is it plausible? | ||
#**Biopsies in negative prostatectomies ''or'' minimal cancer prostatectomies usually have a small volume of low grade cancer. | #**Biopsies in negative prostatectomies ''or'' minimal cancer prostatectomies usually have a small volume of low grade cancer. | ||
#**A negative prostatectomy with high-grade cancer on biopsy ''or'' a large volume of disease on biopsy should prompt identity testing.<ref name=pmid15767799>{{Cite journal | last1 = Cao | first1 = D. | last2 = Hafez | first2 = M. | last3 = Berg | first3 = K. | last4 = Murphy | first4 = K. | last5 = Epstein | first5 = JI. | title = Little or no residual prostate cancer at radical prostatectomy: vanishing cancer or switched specimen?: a microsatellite analysis of specimen identity. | journal = Am J Surg Pathol | volume = 29 | issue = 4 | pages = 467-73 | month = Apr | year = 2005 | doi = | PMID = 15767799 }} | #**A negative prostatectomy with high-grade cancer on biopsy ''or'' a large volume of disease on biopsy should prompt [[identity testing]].<ref name=pmid15767799>{{Cite journal | last1 = Cao | first1 = D. | last2 = Hafez | first2 = M. | last3 = Berg | first3 = K. | last4 = Murphy | first4 = K. | last5 = Epstein | first5 = JI. | title = Little or no residual prostate cancer at radical prostatectomy: vanishing cancer or switched specimen?: a microsatellite analysis of specimen identity. | journal = Am J Surg Pathol | volume = 29 | issue = 4 | pages = 467-73 | month = Apr | year = 2005 | doi = | PMID = 15767799 }}</ref> | ||
</ref> | |||
#Submit prostate in total (if not already done). | #Submit prostate in total (if not already done). | ||
#[[Levels]] (x3) on all prostate blocks.<ref name=pmid22032574/> | #[[Levels]] (x3) on all prostate blocks.<ref name=pmid22032574/> | ||
Latest revision as of 11:24, 1 May 2014
- Vanishing prostate cancer redirects here.
Negative prostatectomy, also radical prostatectomy without cancer, occasionally happens.
General
- Seen in approximately 1% of prostatectomies.[1]
Work-up
- Review biopsy if available.
- Is it plausible?
- Biopsies in negative prostatectomies or minimal cancer prostatectomies usually have a small volume of low grade cancer.
- A negative prostatectomy with high-grade cancer on biopsy or a large volume of disease on biopsy should prompt identity testing.[2]
- Is it plausible?
- Submit prostate in total (if not already done).
- Levels (x3) on all prostate blocks.[1]
- Flip the (prostate tissue) blocks and do levels (x3).[1]
See also
References
- ↑ 1.0 1.1 1.2 Kosarac, O.; Zhai, QJ.; Shen, S.; Takei, H.; Ro, JY.; Ayala, AG. (Nov 2011). "Minimal or no residual prostatic adenocarcinoma on radical prostatectomy: a 5-year experience with vanishing carcinoma phenomenon.". Arch Pathol Lab Med 135 (11): 1466-70. doi:10.5858/arpa.2010-0132-OA. PMID 22032574.
- ↑ Cao, D.; Hafez, M.; Berg, K.; Murphy, K.; Epstein, JI. (Apr 2005). "Little or no residual prostate cancer at radical prostatectomy: vanishing cancer or switched specimen?: a microsatellite analysis of specimen identity.". Am J Surg Pathol 29 (4): 467-73. PMID 15767799.