Difference between revisions of "CNS cytopathology"
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*** [http://www.msdlatinamerica.com/ebooks/DiagnosticNeuropathologySmears/files/cf76aad0d9dab70c99b93186ca8b3ad4.gif Stringy processes - glial tumour (msdlatinamerica.com)].<ref name=latinam>URL: [http://www.msdlatinamerica.com/ebooks/DiagnosticNeuropathologySmears/sid117213.html http://www.msdlatinamerica.com/ebooks/DiagnosticNeuropathologySmears/sid117213.html]. Accessed on: 2 November 2010.</ref> | *** [http://www.msdlatinamerica.com/ebooks/DiagnosticNeuropathologySmears/files/cf76aad0d9dab70c99b93186ca8b3ad4.gif Stringy processes - glial tumour (msdlatinamerica.com)].<ref name=latinam>URL: [http://www.msdlatinamerica.com/ebooks/DiagnosticNeuropathologySmears/sid117213.html http://www.msdlatinamerica.com/ebooks/DiagnosticNeuropathologySmears/sid117213.html]. Accessed on: 2 November 2010.</ref> | ||
*** [http://www.msdlatinamerica.com/ebooks/DiagnosticNeuropathologySmears/files/59f74df1106573dcdea73be7febff2aa.gif Glial tumour mimicing a carcinoma (msdlatinamerica.com)].<ref name=latinam>URL: [http://www.msdlatinamerica.com/ebooks/DiagnosticNeuropathologySmears/sid117213.html http://www.msdlatinamerica.com/ebooks/DiagnosticNeuropathologySmears/sid117213.html]. Accessed on: 2 November 2010.</ref> | *** [http://www.msdlatinamerica.com/ebooks/DiagnosticNeuropathologySmears/files/59f74df1106573dcdea73be7febff2aa.gif Glial tumour mimicing a carcinoma (msdlatinamerica.com)].<ref name=latinam>URL: [http://www.msdlatinamerica.com/ebooks/DiagnosticNeuropathologySmears/sid117213.html http://www.msdlatinamerica.com/ebooks/DiagnosticNeuropathologySmears/sid117213.html]. Accessed on: 2 November 2010.</ref> | ||
Notes: | |||
*Crush artifact (in smear preparation) can mimic glial processes. | |||
**Crush artifact vs. real glial processes: | |||
***No glial processes run perpendicular to the direction of smear. | |||
***Crushed/elongated nuclei are present in artifactual processes. | |||
<!-- *** something i forgot --> | |||
===Metastatic carcinoma=== | |||
*[http://moon.ouhsc.edu/kfung/JTY1/NeuroTest/_derived/Q92-Ans.htm_txt_SampleQ92.gif Squamous cell carcinoma (ouhsc.edu)].<ref>URL: [http://moon.ouhsc.edu/kfung/JTY1/NeuroTest/Q92-Ans.htm http://moon.ouhsc.edu/kfung/JTY1/NeuroTest/Q92-Ans.htm]. Accessed on: 3 November 2010.</ref> | |||
*[http://moon.ouhsc.edu/kfung/JTY1/NeuroTest/Images/SampleQ50.gif Adenocarcioma (ouhsc.edu)]. | |||
*[http://moon.ouhsc.edu/kfung/JTY1/NeuroTest/Images/SampleQ59.gif Small cell carcinoma (ouhsc.edu)]. | |||
==Things that don't smear well== | ==Things that don't smear well== | ||
Revision as of 02:57, 4 November 2010
CNS cytopathology is a subset of neuropathology and cytopathology.
An introduction to cytopathology is in the cytopathology article. Cerebrospinal (CSF) specimens are dealt with in a separate article called CSF cytopathology.
Basic approach
| CNS cytology | |||||||||||||||||||||||||||||||||||||||||
| Tumour | Non-tumour | ||||||||||||||||||||||||||||||||||||||||
| Glial | Non-glial | Infectious | Non-infectious | ||||||||||||||||||||||||||||||||||||||
Glial vs non-glial:
- Glial has glial strands (stringy processes) ~ 1-2 micrometers thick.
Notes:
- Crush artifact (in smear preparation) can mimic glial processes.
- Crush artifact vs. real glial processes:
- No glial processes run perpendicular to the direction of smear.
- Crushed/elongated nuclei are present in artifactual processes.
- Crush artifact vs. real glial processes:
Metastatic carcinoma
- Squamous cell carcinoma (ouhsc.edu).[2]
- Adenocarcioma (ouhsc.edu).
- Small cell carcinoma (ouhsc.edu).
Things that don't smear well
See also
References
- ↑ 1.0 1.1 URL: http://www.msdlatinamerica.com/ebooks/DiagnosticNeuropathologySmears/sid117213.html. Accessed on: 2 November 2010.
- ↑ URL: http://moon.ouhsc.edu/kfung/JTY1/NeuroTest/Q92-Ans.htm. Accessed on: 3 November 2010.
- ↑ 3.0 3.1 Ironside JW (August 1994). "Update on central nervous system cytopathology. II. Brain smear technique". J. Clin. Pathol. 47 (8): 683–8. PMC 502135. PMID 7962615. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC502135/.