Difference between revisions of "Radiation changes"

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*+/-Fibrosis (chronic change).
*+/-Fibrosis (chronic change).
*+/-Edema (acute change).
*+/-Edema (acute change).
DDx:
*[[Pleomorphic tumours]].


==See also==
==See also==

Revision as of 06:40, 25 September 2013

Radiation changes, also radiation effect, are seen occasionally by pathologists. They are usually a result of prior treatments.

Gross

  • +/-Fibrotic appearing tissue.

Microscopic

Features:[1]

  • Cytoplasmic vacuolation - usually abundant.
  • Nucleus:
    • Enlarged nucleus - but normal NC ratio.
    • No nuclear membrane irregularies.
    • Chromatin: "smudgy".
    • +/-Multinucleation.
  • +/-Fibrosis (chronic change).
  • +/-Edema (acute change).

DDx:

See also

References

  1. ↑ Gupta, S.; Mukherjee, K.; Gupta, YN.; Kumar, M. (Aug 1987). "Sequential radiation changes in cytology of vaginal smears in carcinoma of cervix uteri during radiotherapy.". Int J Gynaecol Obstet 25 (4): 303-8. PMID 2887465.
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