Difference between revisions of "Sarcoidosis"
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*In lung: interstitial location. | *In lung: interstitial location. | ||
Images | ===Images=== | ||
<gallery> | |||
Image:Asteroid_body_intermed_mag.jpg | Sarcoidosis - lung. (WC) | |||
Image:Asteroid_body_very_high_mag.jpg | Granulomata in sarcoidosis with asteroid bodies. (WC) | |||
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www: | |||
*[http://path.upmc.edu/cases/case412.html Sarcoidosis - several images (upmc.edu)]. | |||
*[http://path.upmc.edu/cases/case517.html Neurosarcoidosis - several images (upmc.edu)]. | |||
==Stains== | ==Stains== | ||
Revision as of 12:52, 25 August 2013
Sarcoidosis is non-necrotizing granulomatous disease of unknown etiology. It classically associated with (pulmonary) hilar lymphadenopathy. It may be found in almost any organ, e.g. heart, appendix.
General
- Diagnosis of exclusion - infection must be excluded.
- Radiologic differential diagnosis includes carcinomatosis.[1]
Microscopic
Features:
- Granulomata, well-formed, non-necrotizing.
- Usu. minimal (lymphoid) inflammation; sarcoid granulomas are known as "naked granulomas".[2]
- In lung: interstitial location.
Images
Sarcoidosis - lung. (WC)
Granulomata in sarcoidosis with asteroid bodies. (WC)
www:
Stains
- ZN -ve.
- PASD -ve.
- GMS -ve.
Note:
- Done to r/o infection.
See also
References
- ↑ URL: http://www.radiologyassistant.nl/en/46b480a6e4bdc. Accessed on: 23 May 2010.
- ↑ Brinster, NK. (Nov 2008). "Dermatopathology for the surgical pathologist: a pattern-based approach to the diagnosis of inflammatory skin disorders (part II).". Adv Anat Pathol 15 (6): 350-69. doi:10.1097/PAP.0b013e31818b1ac6. PMID 18948765.