Difference between revisions of "Uterine tubes"
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==Salpingitis isthmica nodosa== | ==Salpingitis isthmica nodosa== | ||
*Abbreviated ''SIN''. | *Abbreviated ''SIN''. | ||
*[[AKA]] ''adenosalpingitis'',<ref>Stedman's Medical Dictionary. 27th Ed. Lippincott Williams & Wilkins.</ref> and ''diverticulosis of the Fallopian tubes''.<ref>URL: [http://www.medcyclopaedia.com/library/topics/volume_iv_2/s/salpingitis_isthmica_nodosa.aspx http://www.medcyclopaedia.com/library/topics/volume_iv_2/s/salpingitis_isthmica_nodosa.aspx]. Accessed on: 28 July 2010.</ref> | |||
===General=== | ===General=== | ||
*Associated with infertility and [[ectopic pregnancy]].<ref name=pmid8405510>{{Cite journal | last1 = Jenkins | first1 = CS. | last2 = Williams | first2 = SR. | last3 = Schmidt | first3 = GE. | title = Salpingitis isthmica nodosa: a review of the literature, discussion of clinical significance, and consideration of patient management. | journal = Fertil Steril | volume = 60 | issue = 4 | pages = 599-607 | month = Oct | year = 1993 | doi = | PMID = 8405510 }}</ref> | |||
*Associated with infertility and ectopic pregnancy.<ref name=pmid8405510>{{Cite journal | last1 = Jenkins | first1 = CS. | last2 = Williams | first2 = SR. | last3 = Schmidt | first3 = GE. | title = Salpingitis isthmica nodosa: a review of the literature, discussion of clinical significance, and consideration of patient management. | journal = Fertil Steril | volume = 60 | issue = 4 | pages = 599-607 | month = Oct | year = 1993 | doi = | PMID = 8405510 }}</ref> | |||
*SIN is uncommonly bilateral.<ref name=pmid1757522>{{Cite journal | last1 = Skibsted | first1 = L. | last2 = Sperling | first2 = L. | last3 = Hansen | first3 = U. | last4 = Hertz | first4 = J. | title = Salpingitis isthmica nodosa in female infertility and tubal diseases. | journal = Hum Reprod | volume = 6 | issue = 6 | pages = 828-31 | month = Jul | year = 1991 | doi = | PMID = 1757522 }}</ref> | *SIN is uncommonly bilateral.<ref name=pmid1757522>{{Cite journal | last1 = Skibsted | first1 = L. | last2 = Sperling | first2 = L. | last3 = Hansen | first3 = U. | last4 = Hertz | first4 = J. | title = Salpingitis isthmica nodosa in female infertility and tubal diseases. | journal = Hum Reprod | volume = 6 | issue = 6 | pages = 828-31 | month = Jul | year = 1991 | doi = | PMID = 1757522 }}</ref> | ||
Revision as of 01:15, 31 January 2012
Uterine tubes, aka Fallopian tubes, serve as a connection the ovary and uterus. It is where fertilization usually takes place.
This was ignored in the past... current thinking is that it may be the real culprit in what is often labeled as "ovarian cancer".[1]
Normal
Architecture:
- Finger-like projections into the lumen.
Cells:
- Ciliated cells.
- Columnar.
- Eosinophilic cytoplasm.
- Peg cells.
- Nucleus more luminal.
- Nuclei stick-out like a golf tee.
- Nucleus more luminal.
Images:
Salpingitis
- Also suppurative salpingitis.
- Also granulomatous salpingitis.
General
- Benign.
- May be part of pelvic inflammatory disease.
Microscopic
Features:
- Inflammatory cells:
- Neutrophils = acute.
- Lymphocytes and plasma cells = chronic.
- +/-Granulomas; known as granulomatous salpingitis.
- +/-Clusters of neutrophils = abscess; known as suppurative salpingitis.
Images:
- Salpingitis - low mag. (WC).
- Salpingitis - high mag. (WC).
- Granulomatous salpingitis - intermed mag. (WC).
- Granulomatous salpingitis - high mag. (WC).
Stains
If organisms are seen on routine stains:
- Gram stain +ve/-ve.
Granulomatous inflammation:
- Ziehl-Neelsen stain +ve/-ve.
- GMS stain +ve/-ve.
- PASD stain +ve/-ve.
Adenofibroma
General
- Rare.[3]
- More frequently seen than in the past -- presumably as pathologists are looking more closely at the Fallopian tube.
- Cannot be disguished from ovarian adenofibroma.[3]
Gross
- Solid, nodular.
Microscopic
Features:[3]
- Stroma + glandular elements.
- Glandular elements: secretory cells and ciliated cells.
IHC
Features:
- Stroma:[3]
- CD10 +ve.
- Inhibin +ve.
Salpingitis isthmica nodosa
General
- Associated with infertility and ectopic pregnancy.[6]
- SIN is uncommonly bilateral.[7]
Diagnosis (clinical):
- Hysterosalpingography.[8]
- Finding: diverticula.
Notes:
- The male cousin of this is: vasitis nodosa.
Microscopic
Features:[9]
- Nodular thickening of the tunica muscularis of the isthmic portion.
- Cystically dilated glands.
- +/-Complete obliteration of tubal lumen.
Images:
Adenomatoid tumour
See: Adenomatoid tumours (uterine tumours).
General
- Relatively common tumour of the fallopian tube.[10]
Microscopic
See: Adenomatoid tumours (uterine tumours).
See also
References
- ↑ Hirst, JE.; Gard, GB.; McIllroy, K.; Nevell, D.; Field, M. (Jul 2009). "High rates of occult fallopian tube cancer diagnosed at prophylactic bilateral salpingo-oophorectomy.". Int J Gynecol Cancer 19 (5): 826-9. doi:10.1111/IGC.0b013e3181a1b5dc. PMID 19574767.
- ↑ URL: http://faculty.une.edu/com/abell/histo/histolab3f.htm. Accessed on: 18 October 2011.
- ↑ 3.0 3.1 3.2 3.3 Bossuyt, V.; Medeiros, F.; Drapkin, R.; Folkins, AK.; Crum, CP.; Nucci, MR. (Jul 2008). "Adenofibroma of the fimbria: a common entity that is indistinguishable from ovarian adenofibroma.". Int J Gynecol Pathol 27 (3): 390-7. doi:10.1097/PGP.0b013e3181639a82. PMID 18580316.
- ↑ Stedman's Medical Dictionary. 27th Ed. Lippincott Williams & Wilkins.
- ↑ URL: http://www.medcyclopaedia.com/library/topics/volume_iv_2/s/salpingitis_isthmica_nodosa.aspx. Accessed on: 28 July 2010.
- ↑ Jenkins, CS.; Williams, SR.; Schmidt, GE. (Oct 1993). "Salpingitis isthmica nodosa: a review of the literature, discussion of clinical significance, and consideration of patient management.". Fertil Steril 60 (4): 599-607. PMID 8405510.
- ↑ Skibsted, L.; Sperling, L.; Hansen, U.; Hertz, J. (Jul 1991). "Salpingitis isthmica nodosa in female infertility and tubal diseases.". Hum Reprod 6 (6): 828-31. PMID 1757522.
- ↑ URL: http://radiology.rsna.org/content/154/3/597.abstract. Accessed on: 28 July 2010.
- ↑ Chawla, N.; Kudesia, S.; Azad, S.; Singhal, M.; Rai, SM.. "Salpingitis isthmica nodosa.". Indian J Pathol Microbiol 52 (3): 434-5. doi:10.4103/0377-4929.55019. PMID 19679986.
- ↑ Christensen C (1990). "Adenomatoid tumors of the uterus". Eur. J. Gynaecol. Oncol. 11 (2): 85–9. PMID 2199199.