Difference between revisions of "Worst pattern of invasion"
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==General== | ==General== | ||
*WPOI is predictive of disease free survival in oral cancer.<ref name=pmid29672550/> | *WPOI is predictive of disease free survival in oral cancer.<ref name=pmid29672550/> | ||
WPOI is described as five patterns - but generally divided into two (prognostic) groups: | |||
*WPOI 1-4: better prognosis. | |||
*WPOI 5: poor prognosis. | |||
==Definition of WPOI 5== | |||
WPOI 5 is defined as >=1 mm normal tissue between two tumour masses.<ref>{{cite journal |authors=Sinha N, Rigby MH, McNeil ML, Taylor SM, Trites JR, Hart RD, Bullock MJ |title=The histologic risk model is a useful and inexpensive tool to assess risk of recurrence and death in stage I or II squamous cell carcinoma of tongue and floor of mouth |journal=Mod Pathol |volume=31 |issue=5 |pages=772–779 |date=May 2018 |pmid=29393297 |doi=10.1038/modpathol.2017.183 |url=}}</ref> | |||
==See also== | ==See also== | ||
*[[Tumour budding]]. | *[[Tumour budding]]. | ||
*[[Spread through air spaces]]. | |||
==References== | ==References== | ||
Latest revision as of 20:00, 18 October 2023
Worst pattern of invasion, abbreviated WPOI, is schema for classifying tumour morphologic patterns with the goal of predicting tumour behaviour.[1]
General
- WPOI is predictive of disease free survival in oral cancer.[1]
WPOI is described as five patterns - but generally divided into two (prognostic) groups:
- WPOI 1-4: better prognosis.
- WPOI 5: poor prognosis.
Definition of WPOI 5
WPOI 5 is defined as >=1 mm normal tissue between two tumour masses.[2]
See also
References
- ↑ 1.0 1.1 Shimizu S, Miyazaki A, Sonoda T, Koike K, Ogi K, Kobayashi JI, Kaneko T, Igarashi T, Ueda M, Dehari H, Miyakawa A, Hasegawa T, Hiratsuka H (2018). "Tumor budding is an independent prognostic marker in early stage oral squamous cell carcinoma: With special reference to the mode of invasion and worst pattern of invasion". PLoS One 13 (4): e0195451. doi:10.1371/journal.pone.0195451. PMC 5909609. PMID 29672550. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909609/.
- ↑ Sinha N, Rigby MH, McNeil ML, Taylor SM, Trites JR, Hart RD, Bullock MJ (May 2018). "The histologic risk model is a useful and inexpensive tool to assess risk of recurrence and death in stage I or II squamous cell carcinoma of tongue and floor of mouth". Mod Pathol 31 (5): 772–779. doi:10.1038/modpathol.2017.183. PMID 29393297.