Difference between revisions of "Eosinophilic cholecystitis"

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{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Image      = Eosinophilic cholecystitis -- low mag.jpg
| Width      =
| Caption    = Eosinophilic cholecystitis. [[H&E stain]]. (WC)
| Synonyms  =
| Micro      = gallbladder wall with inflammatory infiltrate that is >90% [[eosinophil]]s
| Subtypes  = (subtype of acute cholecystitis)
| LMDDx      = [[acute cholecystitis]] with eosinophils
| Stains    =
| IHC        =
| EM        =
| Molecular  =
| IF        =
| Gross      =
| Grossing  =
| Staging    =
| Site      = [[gallbladder]]
| Assdx      = eosinophilic cholangitis, hypereosinophilic syndromes, parasitic infection
| Syndromes  =
| Clinicalhx =
| Signs      = see ''[[acute cholecystitis]]''
| Symptoms  =
| Prevalence = rare - case reports
| Bloodwork  = +/-eosinophilia
| Rads      =
| Endoscopy  =
| Prognosis  = benign
| Other      =
| ClinDDx    = [[acute cholecystitis]]
| Tx        = cholecystectomy
}}
'''Eosinophilic cholecystitis''' is a rare type of [[cholecystitis]].
'''Eosinophilic cholecystitis''' is a rare type of [[cholecystitis]].


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*Eosinophilic cholangitis.
*Eosinophilic cholangitis.
*Hypereosinophilic syndromes (HES).
*Hypereosinophilic syndromes (HES).
*Parasitic infestations.
*Parasitic infection.


==Microscopic==
==Microscopic==
Features:
Features:
*Gallbladder wall with inflammtory infiltrate that is >90% eosinophils.<ref name=pmid17522376>{{Cite journal  | last1 = Shakov | first1 = R. | last2 = Simoni | first2 = G. | last3 = Villacin | first3 = A. | last4 = Baddoura | first4 = W. | title = Eosinophilic cholecystitis, with a review of the literature. | journal = Ann Clin Lab Sci | volume = 37 | issue = 2 | pages = 182-5 | month =  | year = 2007 | doi =  | PMID = 17522376 }}</ref><ref name=pmid24638193>{{Cite journal  | last1 = Choudhury | first1 = M. | last2 = Pujani | first2 = M. | last3 = Katiyar | first3 = Y. | last4 = Jyotsna | first4 = PL. | last5 = Rautela | first5 = A. | title = Idiopathic eosinophilic cholecystitis with cholelithiasis: a report of two cases. | journal = Turk Patoloji Derg | volume = 30 | issue = 2 | pages = 142-4 | month =  | year = 2014 | doi = 10.5146/tjpath.2014.01235 | PMID = 24638193 }}</ref>
*Gallbladder wall with inflammatory infiltrate that is >90% eosinophils.<ref name=pmid17522376>{{Cite journal  | last1 = Shakov | first1 = R. | last2 = Simoni | first2 = G. | last3 = Villacin | first3 = A. | last4 = Baddoura | first4 = W. | title = Eosinophilic cholecystitis, with a review of the literature. | journal = Ann Clin Lab Sci | volume = 37 | issue = 2 | pages = 182-5 | month =  | year = 2007 | doi =  | PMID = 17522376 }}</ref><ref name=pmid24638193>{{Cite journal  | last1 = Choudhury | first1 = M. | last2 = Pujani | first2 = M. | last3 = Katiyar | first3 = Y. | last4 = Jyotsna | first4 = PL. | last5 = Rautela | first5 = A. | title = Idiopathic eosinophilic cholecystitis with cholelithiasis: a report of two cases. | journal = Turk Patoloji Derg | volume = 30 | issue = 2 | pages = 142-4 | month =  | year = 2014 | doi = 10.5146/tjpath.2014.01235 | PMID = 24638193 }}</ref>


DDx:
DDx:
*[[Acute cholecystitis]].
*[[Acute cholecystitis]].
===Images===
<gallery>
Image: Eosinophilic cholecystitis -- extremely low mag.jpg | EC - extremely low mag. (WC)
Image: Eosinophilic cholecystitis -- very low mag.jpg | EC - very low mag. (WC)
Image: Eosinophilic cholecystitis -- low mag.jpg | EC - low mag. (WC)
Image: Eosinophilic cholecystitis -- intermed mag.jpg | EC - intermed. mag. (WC)
Image: Eosinophilic cholecystitis -- high mag.jpg | EC - high mag. (WC)
Image: Eosinophilic cholecystitis - alt -- very low mag.jpg | EC - very low mag. (WC)
Image: Eosinophilic cholecystitis - alt -- low mag.jpg | EC - low mag. (WC)
</gallery>


==Sign out==
==Sign out==
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Comment:  
Comment:  
Eosinophilic cholecystitis may be idiopathic or associated with other conditions characterized by eosinophilia, including but not limited to parasitic infections and hypereosinophilic syndromes. Clinical correlation is required.
</pre>
===Verbose===
<pre>
Gallbladder, Cholecystectomy:
    - Eosinophilic cholecystitis and cholelithiasis, see comment.
Comment:
The histopathologic diagnosis of eosinophilic cholecystitis is in keeping with the clinical impression of acute cholecystitis.
Eosinophilic cholecystitis may be idiopathic or associated with other conditions characterized by eosinophilia, including but not limited to parasitic infections and hypereosinophilic syndromes. Clinical correlation is required.
Eosinophilic cholecystitis may be idiopathic or associated with other conditions characterized by eosinophilia, including but not limited to parasitic infections and hypereosinophilic syndromes. Clinical correlation is required.
</pre>
</pre>

Latest revision as of 16:13, 10 March 2018

Eosinophilic cholecystitis
Diagnosis in short

Eosinophilic cholecystitis. H&E stain. (WC)
LM gallbladder wall with inflammatory infiltrate that is >90% eosinophils
Subtypes (subtype of acute cholecystitis)
LM DDx acute cholecystitis with eosinophils
Site gallbladder
Associated Dx eosinophilic cholangitis, hypereosinophilic syndromes, parasitic infection
Signs see acute cholecystitis
Prevalence rare - case reports
Blood work +/-eosinophilia
Prognosis benign
Clin. DDx acute cholecystitis
Treatment cholecystectomy

Eosinophilic cholecystitis is a rare type of cholecystitis.

General

Clinical associations:[1][3]

  • Eosinophilic cholangitis.
  • Hypereosinophilic syndromes (HES).
  • Parasitic infection.

Microscopic

Features:

  • Gallbladder wall with inflammatory infiltrate that is >90% eosinophils.[1][3]

DDx:

Images

  • EC - extremely low mag. (WC)

  • EC - very low mag. (WC)

  • EC - low mag. (WC)

  • EC - intermed. mag. (WC)

  • EC - high mag. (WC)

  • EC - very low mag. (WC)

  • EC - low mag. (WC)

Sign out

Gallbladder, Cholecystectomy:
- Eosinophilic cholecystitis and cholelithiasis, see comment.

Comment: 
Eosinophilic cholecystitis may be idiopathic or associated with other conditions characterized by eosinophilia, including but not limited to parasitic infections and hypereosinophilic syndromes. Clinical correlation is required.

Verbose

Gallbladder, Cholecystectomy:
     - Eosinophilic cholecystitis and cholelithiasis, see comment.

Comment:
The histopathologic diagnosis of eosinophilic cholecystitis is in keeping with the clinical impression of acute cholecystitis.

Eosinophilic cholecystitis may be idiopathic or associated with other conditions characterized by eosinophilia, including but not limited to parasitic infections and hypereosinophilic syndromes. Clinical correlation is required.

See also

References

  1. ↑ 1.0 1.1 1.2 Shakov, R.; Simoni, G.; Villacin, A.; Baddoura, W. (2007). "Eosinophilic cholecystitis, with a review of the literature.". Ann Clin Lab Sci 37 (2): 182-5. PMID 17522376.
  2. ↑ del-Moral-Martínez, M.; Barrientos-Delgado, A.; Crespo-Lora, V.; Cervilla-Sáez-de-Tejada, ME.; Salmerón-Escobar, J. (Jan 2015). "Eosinophilic cholecystitis: an infrequent cause of acute cholecystitis.". Rev Esp Enferm Dig 107 (1): 45-7. PMID 25603333.
  3. ↑ 3.0 3.1 Choudhury, M.; Pujani, M.; Katiyar, Y.; Jyotsna, PL.; Rautela, A. (2014). "Idiopathic eosinophilic cholecystitis with cholelithiasis: a report of two cases.". Turk Patoloji Derg 30 (2): 142-4. doi:10.5146/tjpath.2014.01235. PMID 24638193.
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